Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
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Sublingual Granular Cell Tumor in a Dog

개의 혀 밑에서 발생한 과립세포종

  • Park, Jun-Won (College of Veterinary Medicine, Seoul National University) ;
  • Jee, Hyang (College of Veterinary Medicine, Seoul National University) ;
  • Oh, Won-Seok (NeoDin Veterinary Science Institute) ;
  • Kim, Eun-Ok (NeoDin Veterinary Science Institute) ;
  • Youn, Sin-Keun (Dr.Youn's Animal Hospital) ;
  • Woo, Gye-Hyeong (National Veterinary Research Institute and Quarantine Service) ;
  • Kim, Dae-Yong (College of Veterinary Medicine, Seoul National University)
  • Accepted : 2010.06.16
  • Published : 2010.08.30
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Abstract

Granular cell tumor was described in a 7-year-old male Miniature Pinscher. Sublingual mass was surgically removed and submitted for diagnosis. The mass was about 1.8 cm in diameter, firm, tan, and ulcerated. On histopathology, the mass was unencapsulated and infiltrated adjacent tissue and consisted of nest or sheet of round to polygonal, and occasional spindle-shaped cells. The neoplastic cells contain large amount of eosinophilic granular materials in the cytoplasm. Immunohistochemically, the neoplastic cells were positive to neuron-specific enolase but were negative to S-100. The cytoplasmic eosinophilic granules were positive to PAS but were negative to PTAH methods. Based on these results, the mass was diagnosed as sublingual granular cell tumor. No recurrence or metastasis was noted so far since surgery.

Keywords

References

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