대한치과마취과학회지 (Journal of The Korean Dental Society of Anesthesiology)

  • 제10권1호
  • /
  • Pages.50-53
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  • 2010
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  • 1598-4044(pISSN)
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  • 2383-7039(eISSN)
대한치과마취과학회 (The Korean Dental Society of Anesthsiology)
권호 표지

Propofol에 의한 전신마취 후 회복 시 발생한 근경련 -증례 보고-

Persistent Seizure after Propofol-Induced General Anesthesia in Recovery Room -A Case Report-

  • 김병환 (전남대학교 치의학전문대학원 마취과학교실) ;
  • 정성수 (전남대학교 치의학전문대학원 마취과학교실)
  • Kim, Byung-Hwan (Department of Anesthesiology, School of Dentistry Chonnam National University) ;
  • Chung, Sung-Su (Department of Anesthesiology, School of Dentistry Chonnam National University)
  • 투고 : 2010.06.09
  • 심사 : 2010.06.20
  • 발행 : 2010.06.27
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초록

There are a few case reports describing persistent seizure following propofol. A 45-year-old female underwent operation of mastoidectomy and tympanoplasty. She had no personal or family history of epilepsy. Anesthesia was induced with propofol and rocuronium, and maintained with sevoflurane-remifentanil after tracheal intubation. Any event was not noted during surgery. Seizure-like movement and shivering were developed after surgery in recovery room. Symptom was relieved by benzodiazepines, especially lorazepam. She was discharged in the 9th postoperative days without any sequelae.

키워드

참고문헌

  1. Barash PG, Cullen BF, Stoelting RK, Cahalan MK, Stock MC: Clinical anesthesia. 6th ed, Philadelphia, Lippincott Williams & Wilkins. 2009, pp 451-3.
  2. Bendiksen A, Larsen LM: Convolusion, ataxia and hallucinations following propofol. Acta Anaesthesiol Scand 1998; 42: 739-41. https://doi.org/10.1111/j.1399-6576.1998.tb05312.x
  3. Beyenburg S, Bauer J, Elger CE: Therapy of generalized tonic-clonic status epilepticus in adulthood. Nervenarzt 2000; 71: 65-77. https://doi.org/10.1007/s001150050010
  4. Bleck TP: Management approaches to prolonged seizure and status epilepticus. Epilepsia 1999; 40: 59-63. https://doi.org/10.1111/j.1528-1157.1999.tb00908.x
  5. Borgeat A: Propofol: pro- or anticonvulsant? Eur J Anaesthesiol Suppl 1997; 15: 17-20.
  6. Coghran D, Price W, Gwinnutt CL: Unilateral convulsion after induction of anesthesia with propofol. Br J Anaesth 1996; 76: 570-2.
  7. Derggren I, Ericksson I: Midazolam for induction of anesthesia in out patient - a comparison with thiopentone. Acta Anesth Scand 1981; 25: 492. https://doi.org/10.1111/j.1399-6576.1981.tb01693.x
  8. Dolin SJ, Smith MB, Solar J, Morris PJ: Does glycine antagonism underlie the excitatory effects of methohexitone and propofol. Br J Anaesth 1992; 68: 523-6. https://doi.org/10.1093/bja/68.5.523
  9. Finley GA, MacManus B, Sampson SE, Fernandez CV, Retallick R: Delayed seizures following sedation with propofol. Can J Anaesth 1993;40: 863-5. https://doi.org/10.1007/BF03009258
  10. Jeon WJ, Noh GJ, Lee BD: Persistent myoclonus after propofol anesthesia - a case report -. Korean J Anesthesiol 2001; 40: 689-91. https://doi.org/10.4097/kjae.2001.40.5.689
  11. Jung JK, Chung MH, Choi YR: Acute posthypoxic myoclonus in recovery room. Kor J Anesthesiol 2008; 54: 339-42. https://doi.org/10.4097/kjae.2008.54.3.339
  12. Lowson S, Gent JP, Goodchild CS: Anticonvulsive properties of propofol and thiopentone: comparison using two tests in laboratory mice. Br J Anaesth 1990; 64: 59-63. https://doi.org/10.1093/bja/64.1.59
  13. Mackenzie JJ, Kapadia F, Grant IS: Propofol infusion for control of status epilepticus. Anaesthesia 1992; 69: 177-81. https://doi.org/10.1093/bja/69.2.177
  14. Makela JP, Iivanainen M, Pienninkeroinen IP, Waitomo O, Lahdensuu M: Seizure associated with propofol anesthesia. Epilepsia 1993; 34: 863-5.
  15. Ries CR, Scoates PJ, Puil E: Opisthotonos following propofol: a nonepileptic perspective and treatmnet strategy. Can J Anaesth 1994; 41: 414-9. https://doi.org/10.1007/BF03009864
  16. Riss J, Cloyd J, Gates J, Collins S: Benzodiazepines in epilepsy: pharmacology and pharmacokinetics. Acta Neurol Scand 2008; 118: 69-86. https://doi.org/10.1111/j.1600-0404.2008.01004.x
  17. Southerland MJ, Burt P: Propofol and seizures. Anesth Intensive Care 1994; 22: 733-7.
  18. Smith M, Smith SJ, Scott CA, Harkness WFJ: Activation of the electrocorticogram by propofol during surgery for epilepsy. Br J Anaesth 1996; 76: 499-502. https://doi.org/10.1093/bja/76.4.499
  19. Swart EL, Zuideveld KP, de Jongh J, Danhof M, Thijs LG, Strack van Schijndel RM: Comparative population pharmacokinetics of lorazepam and midazolam during long-term continuous infusion in critically ill patients. Br J Clin Pharmacol 2004; 57:135-45.
  20. Walder B, Tramer MR, Seeck M: Seizure-like phenomena and propofol. Neurology 2002; 12: 1327-32.
  21. Wood PR, Browne GPR, Pugh S: Propofol infusion for the treatment of status epilepticus. Lancet 1988; i: 480-1.