Randomized, Double-blind, Comparative Clinical Trial on the Efficacy of 4% Articaine and 2% Lidocaine in Inferior Alveolar Nerve Block Anesthesia

하치조신경 전달마취 시 4% 아티카인과 2% 리도카인의 임상적 효과에 관한 비교연구

  • Im, Tae-Yun (Division of Oral and Maxillofacial Surgery, Department of Dentistry, College of Medicine, Hanyang University) ;
  • Hwang, Kyung-Gyun (Division of Oral and Maxillofacial Surgery, Department of Dentistry, College of Medicine, Hanyang University) ;
  • Park, Chang-Joo (Division of Oral and Maxillofacial Surgery, Department of Dentistry, College of Medicine, Hanyang University) ;
  • Kim, Kwang-Soo (Division of Preventive Dentistry, Department of Dentistry, College of Medicine, Hanyang University) ;
  • Oh, Young (Division of Conservative Dentistry, Department of Dentistry, College of Medicine, Hanyang University) ;
  • Han, Ji-Young (Division of Periodontology, Department of Dentistry, College of Medicine, Hanyang University) ;
  • Shim, Kwang-Sup (Division of Oral and Maxillofacial Surgery, Department of Dentistry, College of Medicine, Hanyang University)
  • 임태윤 (한양대학교 의과대학 치과학교실 구강악안면외과) ;
  • 황경균 (한양대학교 의과대학 치과학교실 구강악안면외과) ;
  • 박창주 (한양대학교 의과대학 치과학교실 구강악안면외과) ;
  • 김광수 (한양대학교 의과대학 치과학교실 예방치과) ;
  • 오영 (한양대학교 의과대학 치과학교실 치과보존과) ;
  • 한지영 (한양대학교 의과대학 치과학교실 치주과) ;
  • 심광섭 (한양대학교 의과대학 치과학교실 구강악안면외과)
  • Received : 2010.06.08
  • Accepted : 2010.06.20
  • Published : 2010.06.27

Abstract

Background: Articaine, commercially available in South Korea from 2004, is widely being used for dental treatments. In the surgical extraction of impacted mandibular third molars, one of the most common procedures in oral and maxillofacial surgery, the anesthetic efficacy of 4% articaine and 2% lidocaine, both with 1:100,000 epinephrine, was compared. Methods: A randomized double-blind clinical trial was conducted of 80 patients for bilateral surgical extraction of mandibular third molars with informed consents. One operator carried out the routine surgical procedures using local anesthetic 4% articaine or 2% lidocaine with the same concentration of vasoconstrictor. Latency, duration of anesthesia and the amount of anesthetic solution were recorded. A visual analog scale (VAS) was used to evaluate the intraoperative pain. Results: The pain VAS scores reported similar anesthetic effect with both local anesthetics. Not in the latency of anesthesia and the amount of anesthetic solution, statistically significant difference was found in the mean duration of anesthesia. Conclusions: It was concluded that 4% articaine could offer better or at least the same clinical feasibility compared to 2% lidocaine, particularly in terms of the duration of the local anesthesia for common dental treatments.

Keywords

References

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