The Journal of Internal Korean Medicine (대한한방내과학회지)

The Society of Internal Korean Medicine (대한한방내과학회)
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Clinical Study of 8 Diabetic Patients with Paresthesia

감각이상을 주소로 내원한 당뇨병 환자 8례에 대한 임상보고

  • Kim, Jin-Mi (Dept. of Internal Medicine, College of Oriental Medicine, Dae-Jeon University) ;
  • Cho, Chung-Sik (Dept. of Internal Medicine, College of Oriental Medicine, Dae-Jeon University) ;
  • Kim, Chul-Jung (Dept. of Internal Medicine, College of Oriental Medicine, Dae-Jeon University)
  • 김진미 (대전대학교 한의과대학 신계내과학교실) ;
  • 조충식 (대전대학교 한의과대학 신계내과학교실) ;
  • 김철중 (대전대학교 한의과대학 신계내과학교실)
  • Published : 2010.06.30
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Abstract

Objective : The purpose of this study was to report the effect of Bogijetong-tang on diabetic peripheral neuropathy. Methods : Nine patients who were diagnosed or suspected with diabetic peripheral neuropathy enrolled in this study. They took Bogijetong-tang 2 or 3 times a day and were given acupuncture therapy. To evaluate the therapeutic effect, Visual Analog Scale (VAS) or Total Symptom Score (TSS) were examined at intervals of about 7 days. Result : TSS score decreased an average of 2.74 points and VAS scores decreased an average of 3.67 points. As the pain decreased, accompanied gait disturbance also improved in some patients. Conclusion : Bogijetong-tang is effective in treating diabetic peripheral neuropathy, but study of the concrete mechanism and efficacy is needed.

Keywords

References

  1. Dyck PJ, Kratz KM, Karnes JL, Litchy WJ, Klein R, Pach JM, et al. The prevalence by staged severity of various types of diabetic neuropathy, retinopathy, and neuropathy in a population-based cohort. The Rochester Diabetic Neuropathy Study. Neurology. 1993;43:817-24 https://doi.org/10.1212/WNL.43.4.817
  2. Halat KM, Dennehy CE. Botanicals and Dietary Supplements in Diabetic Peripheral Neuropathy. The Journal of the American Board of Family Practice. 2003;16:47-57. https://doi.org/10.3122/jabfm.16.1.47
  3. Kim JM, Youn SS, An SH, Choi JS, Cho CS, Son CG, et al. Overview of Diabetic Peripheral Neuropathy and Need for Therapeutic Strategy using Traditional Korean Medicine. J Korean Oriental Med. 2009;30(5):127-36.
  4. Sharma S, Chopra K, Kulkarni SK. Effect of insulin and its combination with resveratrol or curcumin in attenuation of diabetic neuropathic pain: participation of nitric oxide and TNFalpha. Phytother Res. 2007;21(3):278-83. https://doi.org/10.1002/ptr.2070
  5. Park SK, Kwon EH, Shin HC, Kang SB. One Case of Diabetic Peripheral Polyneuropathy Improved by Binsosan-gamibang. J Korean Oriental Med. 2005;26(4):935-40.
  6. 전국한의과대학본초학교수 공저. 본초학. 서울: 영림사; 1991, p. 8-15.
  7. 대한당뇨병학회 신경병증 연구회. 당뇨병성 신경병증 진료지침. 2nd edition. Seoul: Korean Diabetes Association; 2007, p. 1-48, 134, 139-40.
  8. 全國韓醫科大學鍼灸․經穴學敎室. 鍼灸學下. 서울: 集文堂; 2004, p. 1266.
  9. Sharma S, Chopra K, Kulkarni SK. Effect of insulin and its combination with resveratrol or curcumin in attenuation of diabetic neuropathic pain: participation of nitric oxide and TNF -alpha. Phytother Res. 2007;21(3):278-83. https://doi.org/10.1002/ptr.2070
  10. John C. Pickups & Gareth Williams. Textbook of Diabetes. 3rd edition. Seoul: KMS; 2006, p. 903, 912.
  11. Jensen TS, Backonja MM, Hernández Jiménez S, Tesfaye S, Valensi P, Ziegler D. New perspectives on the management of diabetic peripheral neuropathic pain. Diab Vasc Dis Res. 2006;3(2):108-19. https://doi.org/10.3132/dvdr.2006.013
  12. Yin Y, Heo SI, Jung MJ, Wang MH. Antioxidant and Antidiabetic Effects of Various Sections of Astragalus membranaceus. Kor J Pharmacogn. 2009;40(1):1-5.
  13. Jang DS, Lee YM, Kim YS, Kim JS. Screening of Korea Traditional Herbal Medicines with Inhibitory Activity on Advanced Glycation End Products (AGEs) Formation. Kor J Pharmacogn. 2006;37(1):48-52.
  14. Lim SM, Ahn JJ, Jo HK, Yoo HR, Kim YS, Seol IC. Effect of Gyehyuldeung Treatments in Peripheral Nerve Regeneration of Rat. Korean J Orient.Int. Med. 2009;30(2):375-87.
  15. 김창민, 신민교, 안덕균, 이정순 등. 中藥大辭典. 서울: 도서출판 정담; 1997, p. 223.
  16. Na HJ, Cha DS, Jeon H. Anti-inflammatory activity of methanol extract isolated from stem bark of Albizia julibrissin. Oriental Pharmacy and Experimental Medicine. 2009;9(2):157-63. https://doi.org/10.3742/OPEM.2009.9.2.157
  17. Choi MS, Kim DG, Lee TK, Kim EY, Rhyu MR. A study on antioxidative and Antihypertensive Effects of the Water Extracts of Albizzia julibrissin. The Journal of Oriental Obstetrics & Gynecology. 2004;17(4):61-72.
  18. Kang KA, Chae SW, Kang DG, Kim JS, Hyun JW. Screening of Antioxidative Effect of Herbal Extracts on Oxidative Stress. Kor. J. Pharmacogn. 2005;36(3):159-63.
  19. Park SM, Zhao RJ, Lee JR, Lee CW, Kim HJ, Kwon YK, et al. Inhibitory Effect of Oyster Conchioloin on Pro-inflammatory Mediator in Lipopolysaccharide;Activated Raw 264.7 Cells. Korean J. Oriental Physiology & Pathology. 2008;22(4):878-83.