Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
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Re-Examination of Blood Vessels of Rat Tail Using Angiographic and Histological Methods

혈관조형술과 조직학적 방법을 이용한 랫드 꼬리의 혈관구조 규명

  • Lee, Kyoung-Sun (Department of Laboratory Animal Medicine, College of Veterinary Medicine, Konkuk University) ;
  • Jeong, Eui-Suk (Department of Laboratory Animal Medicine, College of Veterinary Medicine, Konkuk University) ;
  • Heo, Seung-Ho (Department of Laboratory Animal Medicine, College of Veterinary Medicine, Konkuk University) ;
  • Seo, Jin-Hee (Department of Laboratory Animal Medicine, College of Veterinary Medicine, Konkuk University) ;
  • Lee, Min-Su (Department of Veterinary Diagnostic Imaging, Konkuk University) ;
  • Eom, Ki-Dong (Department of Veterinary Diagnostic Imaging, Konkuk University) ;
  • Choi, Yang-Kyu (Department of Laboratory Animal Medicine, College of Veterinary Medicine, Konkuk University)
  • 이경선 (건국대학교 수의과대학, 실험동물의학교실) ;
  • 정의숙 (건국대학교 수의과대학, 실험동물의학교실) ;
  • 허승호 (건국대학교 수의과대학, 실험동물의학교실) ;
  • 서진희 (건국대학교 수의과대학, 실험동물의학교실) ;
  • 이민수 (건국대학교 방사선 및 영상진단학교실) ;
  • 엄기동 (건국대학교 방사선 및 영상진단학교실) ;
  • 최양규 (건국대학교 수의과대학, 실험동물의학교실)
  • Accepted : 2010.04.01
  • Published : 2010.04.30
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Abstract

Although the tail vessels are frequently used for serial blood sampling in rat, the definition of its vasculature remains in dispute. Herein, we investigated the number of blood vessels in Sprague-Dawley rat tail using angiographic and histological methods. Our results showed rat tail has one dorsal vein, two lateral veins, one ventral artery and one ventral vein. In the conclusion, when deciding which site is best for collecting blood, it is critical to consider the structure and features of the blood vessels to be used. This study will also be helpful for investigators to understand the structure of blood vessels in rat tail.

랫드 꼬리는 연속적인 채혈을 위해서 주로 이용되는 채혈부위로 꼬리 절개법, 꼬리 절단법, 꼬리 천자 등의 방법을 통해 채혈이 이루어지고 있다. 하지만, 랫드 꼬리에 대한 혈관 구조는 아직 잘 밝혀져 있지 않다. 그래서 본 연구에서는 독성학이나 약리학에서 가장 많이 이용되는 폐쇄군인 Sprague-Dawley 랫드 꼬리의 혈관구조 규명하기 위해 혈관조형술과 면역조직학적인 방법을 실시하였다. 그 결과 SD 랫드 꼬리는 한 개의 등쪽 정맥과 두개의 외측정맥, 한쌍의 배쪽 정맥과 동맥이 존재했다. 그러므로, 본 연구는 SD 랫드 꼬리를 이용해서 채혈을 하고자 하는 연구자들이 꼬리의 혈관구조를 이해하고, 그 연구 목적에 맞게 채혈부위와 방법을 선택하는데 도움이 될 것으로 생각된다.

Keywords

References

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