Journal of Preventive Medicine and Public Health

The Korean Society for Preventive Medicine (대한예방의학회)
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Reliability of Covariates in Baseline Survey of a Cohort Study: Epidemiological Investigation on Cancer Risk Among Residents Who Reside Near the Nuclear Power Plants in Korea

코호트 기반 조사 공변수 자료의 신뢰도 평가 연구: 원전주변지역주민 역학조사연구

  • Bae, Sang-Hyuk (Department of Preventive Medicine, College of Medicine, Seoul National University) ;
  • Park, Bo-Young (Department of Preventive Medicine, College of Medicine, Seoul National University) ;
  • Li, Zhong-Min (Institute of Radiation Effect & Epidemiology, Seoul National University Medical Research Centre) ;
  • Ahn, Yoon-Ok (Department of Preventive Medicine, College of Medicine, Seoul National University)
  • 배상혁 (서울대학교 의과대학 예방의학교실) ;
  • 박보영 (서울대학교 의과대학 예방의학교실) ;
  • 이충민 (서울대학교 의학연구원 원자력영향역학연구소) ;
  • 안윤옥 (서울대학교 의과대학 예방의학교실)
  • Received : 2009.09.10
  • Accepted : 2009.11.03
  • Published : 2010.03.31
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Abstract

Objectives: We evaluated the reliability of the possible covariates of the baseline survey data collected for the Epidemiological Investigation on Cancer Risk Among Residents Who Reside Near the Nuclear Power Plants in Korea. Methods: Follow-up surveys were conducted for 477 participants of the cohort at less than 1 year after the initial survey. The mean interval between the initial and follow-up surveys was 282.5 days. Possible covariates were identified by analyzing the correlations with the exposure variable and associations with the outcome variables for all the variables. Logistic regression analysis with stepwise selection was further conducted among the possible covariates to select variables that have covariance with other variables. We considered that these variables can be representing other variables. Seven variables for the males and 3 variables for the females, which had covariance with other possible covariates, were selected as representative variables. The Kappa index of each variable was calculated. Results: For the males, the Kappa indexes were as follow; family history of cancer was 0.64, family history of liver diseases in parents and siblings was 0.56, family history of hypertension in parents and siblings was 0.51, family history of liver diseases was 0.50, family history of hypertension was 0.44, a history of chronic liver diseases was 0.53 and history of pulmonary tuberculosis was 0.36. For females, the Kappa indexes were as follow; family history of cancer was 0.58, family history of hypertension in parents and siblings was 0.56 and family history of hypertension was 0.47. Conclusions: Most of the possible covariates showed good to moderate agreement.

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References

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