Journal of Sasang Constitutional Medicine (사상체질의학회지)

The Society Of Sasang Constitutional Medicine (사상체질의학회)
권호 표지

Anti-Oxidative Effect of Soyangin Hyeongbangpaedok-san Decoction in Kidney and Spleen Cells of Aged Rats

소양인(少陽人) 형방패독산(荊防敗毒散) 전탕액이 노화쥐의 신장과 비장 세포의 항산화능에 미치는 영향

  • Min, Gyeong-Hoon (Dept. of Sasang Constitutional Medicine, college of korean Medicine) ;
  • Ahn, Taek-Won (Dept. of Sasang Constitutional Medicine, college of korean Medicine)
  • 민경훈 (대전대학교 한의과대학 사상체질과) ;
  • 안택원 (대전대학교 한의과대학 사상체질과)
  • Received : 2009.10.22
  • Accepted : 2009.12.02
  • Published : 2010.03.31
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Abstract

1. Objectives: The purpose of this study is to find out the Anti-Oxidative effects of Soyangin Hyeongbangpaedok-san(HBP) in kidney and spleen cells of aged rats. 2. Methods: Aged rats used in this experiment were 6, 52, 68 weeks old. Each age group was divided into three groups again. One group was given no treatment, another group was dosed normal saline and the other group was dosed HBP decoction. The antioxidant effects of HBP decoction were measured by the levels of SOD, GSH, MDA and NO. 3. Results: and Conclusions: 1) The activity of SOD was significantly increased in kidney cells of 68w-HBP group. Deterioration of the activity of SOD in kidney cells was significantly suppressed according to increasing in age of the week. 2) The level of NO was significantly decreased in kidney cells of 68w-HBP group. Deterioration of The level of NO in kidney cells was significantly suppressed according to increasing in age of the week. 3) The activity of SOD was increased in spleen cells of 52w and 68w-HBP group. 4) The level of GSH was significantly increased in spleen cells of 68w-HBP group.

Keywords

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