The Korean Journal of Applied Statistics (응용통계연구)

The Korean Statistical Society (한국통계학회)
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Interpreting Mixtures Using Allele Peak Areas

Mixture에서 봉우리 면적을 활용한 유전자 증거의 해석

  • Received : 20090600
  • Accepted : 20091200
  • Published : 2010.02.28
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Abstract

Mixture is that DNA profiles of samples contain material from more than one contributor, especially common in rape cases. In this situation, first, the method based on enumerating a complete set of possible genotype that may have generated the mixed DNA profile have been studied for interpreting DNA mixtures. More recently, the methods utilizing peak area information to calculate likelihood ratios have been suggested. This study is concerned with the analysis and interpretation of mixed forensic stains using quantitative peak area information and the method of forensic inference for extension of material from more than or equal to three contributors. Finally, the numerical example will be outlined.

형사사건에서 STR(short tandem repeat)을 이용한 개인 식별은 범죄현장에서 발견된 유전자 증거와 용의자의 유전자 검사 결과를 이용하여 평가하게 된다. 특히 범죄현장에서 발견된 유전자 증거 표본에 기여자가 두 명 이상인 경우를 Mixture라고 하며, 이는 강간 등과 같은 사건에서 흔히 볼 수 있다. 이러한 상황에서 법의학적 추론을 위해 유전자 증거 표본을 해석하고자 하는 연구들이 계속되어 왔으며, 최근에는 Mixture에서 발생한 대립유전자의 봉우리 면적을 활용하여 유전자 증거를 해석하기 위한 노력들이 계속되고 있다. 따라서 본 연구에서는 봉우리 변적을 이용하여 유전자 증거 표본을 해석하기 위한 연구 방법들에 대해 살펴볼 것이며, 또한 유전자 증거 표본에 기여한 사람의 수가 세 명 이상안 표본으로 확장시킨 연구를 실시해 볼 것이다. 마지막으로 사례틀 통해 유전자 증거를 해석하는 방법을 살펴보고자 한다.

Keywords

References

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