한국수산과학회지 (Korean Journal of Fisheries and Aquatic Sciences)

  • 제43권1호
  • /
  • Pages.33-38
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  • 2010
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  • 0374-8111(pISSN)
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  • 2287-8815(eISSN)
한국수산과학회 (The Korean Society of Fisheries and Aquatic Science)
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해수 분리 세균 Bacillus sp. DH-9의 항균활성

Antibacterial Activity of Bacillus sp. DH-9 Isolated from Sea Water

  • 김영만 (동의대학교 블루바이오 소재개발 센터) ;
  • 김도균 (동의대학교 생명응용학과) ;
  • 김남희 (동의대학교 생명응용학과) ;
  • 변태환 (동의대학교 생명응용학과) ;
  • 김아라 (동의대학교 생명응용학회) ;
  • 이은우 (동의대학교 생명응용학과) ;
  • 권현주 (동의대학교 생명응용학과) ;
  • 김병우 (동의대학교 생명응용학과)
  • 투고 : 2010.01.15
  • 심사 : 2010.02.22
  • 발행 : 2010.02.28
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초록

Emerging of antibiotic resistance of pathogenic bacteria is now a very serious problem in the clinics to treat the diseases, which have been easy to cure by antibiotic treatments before. Unfortunately, antibiotics developed till now are not effective any more against the resistant bacteria. Lots of efforts to discover new antibiotics having novel and unique structures and functions are really urgent and undergoing in the whole world. In this study, we tried to screen and isolate Same unique bacterial strains producing antibacterial substances from the sea water, which is the poor environment for bacteria 10 make their growing. Three bacterial strains among 916 strains isolated showed inhibition clear zone on the marine agar plate growing pathogenic bacteria including Acinetobacter baumannii, Edwardsiella tarda, Pseudomonas aeruginosa, Staphylococcus aureus, Salmonella enterica. One of them, which was identified as Bacillus sp. DH-9 from 16S rRNA gene analysis, showed especially considerable antibacterial activity against S. aureus which is notorious for methicillin resistant S. aureus (MRSA). The growth of S. aureus was totally inhibited when the supernatant of Bacillus sp. DH-9 culture was treated on.

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