The Journal of Korean Medicine (대한한의학회지)

The Society of Korean Medicine (대한한의학회)
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Effects of Herb Medication on Dry Cough, a Common Side Effect Caused by Angiotensin Converting Enzyme (ACE) Inhibitor

한약치료가 Angiotensin Converting Enzyme Inhibitor를 복용중인 고혈압환자에게 부작용으로 나타나는 건해(乾咳)에 미치는 영향

  • Kim, Hyun-Jin (Department of Oriental Internal Medicine, National Medical Center) ;
  • Kang, Rae-Yeop (Department of Oriental Internal Medicine, National Medical Center) ;
  • Han, Hyo-Jung (Department of Oriental Internal Medicine, National Medical Center) ;
  • Park, Eun-Young (Department of Oriental Internal Medicine, National Medical Center) ;
  • Jang, Jeong-A (Department of Oriental Internal Medicine, National Medical Center) ;
  • Seo, Ho-Seok (Department of Oriental Internal Medicine, National Medical Center) ;
  • Park, So-Ae (Division of Circulatory System, Dept. of Internal Medicine, College of Oriental Medicine, Dae-jeon University) ;
  • Kim, Jin-Won (Department of Oriental Internal Medicine, National Medical Center)
  • 김현진 (국립의료원 한방진료부 한방내과) ;
  • 강래엽 (국립의료원 한방진료부 한방내과) ;
  • 한효정 (국립의료원 한방진료부 한방내과) ;
  • 박은영 (국립의료원 한방진료부 한방내과) ;
  • 장정아 (국립의료원 한방진료부 한방내과) ;
  • 서호석 (국립의료원 한방진료부 한방내과) ;
  • 박소애 (대전대학교 한의과대학 심계내과학교실) ;
  • 김진원 (국립의료원 한방진료부 한방내과)
  • Received : 2009.07.24
  • Accepted : 2009.09.01
  • Published : 2010.01.30
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Abstract

Objectives: In order to confirm a remedial effect and related influence of the clinic treatment by prescribing herb medicines to hypertensives experiencing angiotensin converting enzyme (ACE) inhibitor dosage and suffering from common side effect generally known as dry cough. Methods: 1. We selected the 19 patients who visited National Oriental Medical Center, from August 21, 2007 to August 16, 2008 and suffering from dry cough caused by taking ACE inhibitor, with no other possible diseases causing dry cough. 2. We separated the 19 patients into two groups (Type 1: Bi-Qi hie (脾氣虛) group prescribed Samchuljojung-tang & Type 2: Qi-hie dam-wul (氣虛痰鬱) group prescribed Samsoumgamibang). 3. We then observed the symptom level and post-treatment effect, and recorded changes of dry cough intensity level for each group. Results: 1. Type 1: In the survey of 12 patients, initial level recorded 16.33 at entry diagnosis, and next level meant changing of symptoms, recorded as 2.75 at Stage 1 and reaching 3.33 at Stage 2. 2. Type 2: 7 patients, with initial level recorded as 18.71 at entry diagnosis, and 1.86 at Stage 1 and reaching to 3.29 at Stage 2. 3. No additional prescriptions were issued at Stage 2 or afterwards, and final result indicates that the mean value ended at 3.95 in the total group. Conclusions: It is concluded that there is a significant remedial effect and related influence of the clinic treatment between the Oriental medicine treatment and one of the common side effects of ACE inhibitor, dry cough.

Keywords

References

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