Journal of Microbiology and Biotechnology

  • 제20권6호
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  • Pages.985-987
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  • 2010
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  • 1017-7825(pISSN)
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  • 1738-8872(eISSN)
한국미생물·생명공학회 (The Korean Society for Microbiology and Biotechnology)
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Biotransformation of Bioactive (-)-Mellein by a Marine Isolate of Bacterium Stappia sp.

  • 투고 : 2010.02.09
  • 심사 : 2010.02.17
  • 발행 : 2010.06.28
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초록

The biological transformation of the bioactive dihydroisocoumarin, (-)-mellein, isolated from the marinederived fungus Cladosporium sp., was studied. The preparativescale culture of (-)-mellein with a marine isolate of a bacterium Stappia sp. resulted in the isolation of its oxidized metabolite, (3R,4S)-4-hydroxymellein. The stereostructure of the metabolite obtained was assigned on the basis of detailed physicochemical data analyses.

키워드

참고문헌

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