통합자연과학논문집 (Journal of Integrative Natural Science)

조선대학교 기초과학연구원 (The Basic Science Institute Chosun University)
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Biosensor Based on Distributed Bragg Reflector Photonic Crystals for the Detection of Protein A

  • 정대혁 (단국대학교 응용물리학과)
  • Jung, Daehyuk (Department of Applied Physic, Dankook University)
  • 투고 : 2010.03.04
  • 심사 : 2010.03.20
  • 발행 : 2010.03.31
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초록

The functionalized photonic crystals of porous silicon biosensor was prepared for the application as a label-free biosensor based on distributed Bragg reflector interferometer. Prepared distributed Bragg reflector of porous silicon biosensor displayed sharp reflection in the optical reflective spectra. The mean of construction of molecular architectures on distributed Bragg reflector of porous silicon surfaces was investigated for the step-by-step binding interaction with amines, biotin, avidin, and biotinylated protein A. The subsequent introduction of avidin, and biotinylated protein A resulted in the reflectivity shifted to longer wavelengths, indicative of a change in refractive indices induced by binding of biomolecules.

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