Browse > Article
http://dx.doi.org/10.13160/ricns.2010.3.1.033

Biosensor Based on Distributed Bragg Reflector Photonic Crystals for the Detection of Protein A  

Jung, Daehyuk (Department of Applied Physic, Dankook University)
Publication Information
Journal of Integrative Natural Science / v.3, no.1, 2010 , pp. 33-37 More about this Journal
Abstract
The functionalized photonic crystals of porous silicon biosensor was prepared for the application as a label-free biosensor based on distributed Bragg reflector interferometer. Prepared distributed Bragg reflector of porous silicon biosensor displayed sharp reflection in the optical reflective spectra. The mean of construction of molecular architectures on distributed Bragg reflector of porous silicon surfaces was investigated for the step-by-step binding interaction with amines, biotin, avidin, and biotinylated protein A. The subsequent introduction of avidin, and biotinylated protein A resulted in the reflectivity shifted to longer wavelengths, indicative of a change in refractive indices induced by binding of biomolecules.
Keywords
Porous silicon; Photonic Structure; Biosensor; Red Shift;
Citations & Related Records
연도 인용수 순위
  • Reference
1 P. C. Canham, "Role of Si-H and Si-H2 in the photoluminescence of porous Si", Appl. Phys. Lett, vol. 62, pp. 1099-1101, 1993.   DOI
2 R. L. Smith and S. D. Collins, "Induction of articular cartilage degradation by recombinant interleukin 1 alpha and 1 beta.", J. Appl. Phys. vol. 71, pp. 307-316, 1992.
3 P. C. Searson, Advances in Electrochemical Sciences and Engineering, VCH: Mannheim, Germany, vol. 69, 1994.
4 D. H. Yun, M. J. Song, S. I. Hong, M. S. Kang and N. K. Min, "Highly sensitive and renewable amperometric urea sensor based on self-assembled monolayer using porous silicon substrate", J. Korean Phys. Soc., vol. 47, pp. S445-S449, 2005.
5 U. Gangopadhyay, C. Pramanik, H. Saha, K. Kim, and J. Yi, "Porous silicon as pressure sensing material", J. Korean Phys. Soc. vol. 47, pp. S450-S453, 2005.
6 Y. Y. Li, F. Cunin, J. T.Link, T. Gao, R. E. Betts, S. H. Reiver, V. Chin, S. N. Bhatia and M. J. Sailor, "Polymer replicas of photonic porous silicon for sensing and drug delivery applications", Science vol. 199, pp. 2045-2047, 2003.
7 T. A. Schmedake, F. Cunin, J. R. Link and M. J. Sailor, "Standoff detection of chemicals using porous silicon smart dust particles", Adv. Mater., vol. 14, pp. 1270-1272, 2002.   DOI   ScienceOn
8 S. O. Meade, M. S. Yoon, K. H. Ahn and M. J. Sailor, "Porous silicon photonic crystals as encoded microcarriers" Adv. Mater. vol. 16, pp. 1811-1814, 2004.   DOI   ScienceOn
9 A. Brecht and G. Sens. Gauglitz, Actuators B. vol. 38, no. 1, 1997.
10 J. Janata, M. Josowicz and D. M. Devaney, "Chemical Sensors", Anal. Chem. vol. 70, pp. 179R-208R, 1998.
11 J. Drott, K. Lindstrom, L. Rosengren, T. Laurell, "Porous silicon as the carrier matrix in microstructured enzyme reactors yielding high enzyme activities", J. Micromech. Microeng. vol. 7, pp. 14-23, 1997.   DOI   ScienceOn
12 K. L. Beattie, W. G. Beattie, L. Mengm, S. L. Turner, R. Coral-Vazquez, D. D. Sith, P. M. Mclntyre and D. D. Dao, "Advances in genosensor research", Clin. Chem. vol. 41, 700-706, 1995,.
13 T. Laurell, J. Drott, L. Rosengern and K. Lindstrom, "Enhanced enzyme activity in silicon integrated enzyme reactors utilizing porous silicon as the coupling matrix", Sens. Actuators, B vol. 31, pp. 161-166, 1996.   DOI   ScienceOn
14 V. S.-Y. Lin, K. Motesharei, K.-P. S. Dancil, M. J. Sailor and M. R. Ghadiri, "A porous silicon-based optical interferometric biosensor", Science vol. 278. pp. 840-843, 1997.   DOI   ScienceOn
15 Sailor, M. J. "Properties of porous silicon" Data review Ser. Canham London, no. 18, pp. 364, 1997.