Bulletin of the Korean Chemical Society

Korean Chemical Society (대한화학회)
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Protulactones A and B: Two New Polyketides from the Marine-derived Fungus Aspergillus sp. SF-5044

  • Sohn, Jae-Hak (College of Medical and Life Sciences, Silla University) ;
  • Oh, Hyun-Cheol (College of Medical and Life Sciences, Silla University)
  • Received : 2010.03.02
  • Accepted : 2010.04.20
  • Published : 2010.06.20
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Abstract

Protulactones A (1) and B (2), two new polyketide-derived fungal metabolites, have been isolated from an EtOAc extract of the marine-derived fungus Aspergillus sp. SF-5044 by various chromatographic methods. The structures of 1 and 2 were mainly determined by analysis of the NMR spectroscopic data and MS data, along with chemical methods such as Mosher method. Protulactones A (1) and B (2) are new members of polyketide-derived secondary metabolites, possessing unique ring systems among the fungal metabolites produced by the genus Aspergillus.

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