안압상승의 위험인자로서 체질량지수(BMI)와 허리둘레의 비교

Body Mass Index Compared with Waist Circumference Indicators as a Predictor of Elevated Intraocular Pressure

  • Park, Sang-Shin (Department of Veterinary Integrative Biosciences, College of Veterinary Medicine and Biomedical Sciences, Texas A& M University) ;
  • Lee, Eun-Hee (Department of Visual Optics, Far East University) ;
  • Paek, Domyung (Graduate School of Public Health, Seoul National University) ;
  • Cho, Sung-Il (Graduate School of Public Health, Seoul National University)
  • 투고 : 2010.03.25
  • 심사 : 2010.09.18
  • 발행 : 2010.09.30

초록

목적: 본 연구는 안압 상승의 예측인자로서의 비만 지표인 체질량지수(body mass index: BMI)와 허리둘레 중 어떤 지표가 예측인자로서 더 적절한지를 판단하기 위하여 수행되었다. 방법: 본 연구에 참여한 20세 이상의 성인 458명을 대상으로 분석을 시행하였다. BMI를 삼분위로 층화한 후 허리둘레(삼분위)에 따른 안압을 비교하였으며, 다음으로 허리둘레를 삼분위로 층화한 후 BMI(삼분위)에 따른 안압을 비교하였다. 또한, BMI, 허리둘레와 안압 간의 선형회귀분석을 각각 시행하였다. 결과: 허리둘레 층화 후 BMI에 따른 안압의 증가는 관찰되지 않았지만, BMI $24.9kg/m^2$ 이상의 대상자들에게서는 허리둘레와 안압이 양의 상관관계를 가지는 것을 확인할 수 있었다. 성별과 연령을 보정한 경우에는 허리둘레만이 안압과 유의한 양의 상관관계를 보였고, 여기에 생활변수까지 보정한 다중선형회귀분석결과 BMI와 허리둘레는 모두 안압과 유의한 양의 상관관계를 보였다. 그러나 허리둘레 증가가 안압 상승에 대해서 보다 높은 설명력과 유의수준을 보이는 것으로 평가되었다. 결론: 본 연구결과, BMI와 허리둘레 모두 안압과 양의 상관관계가 있는 것으로 확인되었으며, 허리둘레가 BMI보다 안압에 더 큰 영향을 미치는 것으로 나타났다.

Purpose: The aim of the current study was to compare body mass index (BMI) with waist circumference (WC) as a predictor of elevated intraocular pressure (IOP). Methods: The subjects were consisted of 458 adults, aged 20 year or above, of one community in Kyunggi-do. Mean IOPs were stratified jointly for BMI and WC tertiles. Multi-variate linear regression analysis was also used to compare between BMI and WC. Results: Although any BMI tertiles were not associated with IOP within each tertile of WC, WC tertiles was significantly related to elevation of IOP within the third BMI tertile (${\geq}24.9kg/m^2$). After adjusting for age and sex, only WC showed significant association with IOP. In additional adjustment for lifestyle variables, both BMI and WC were significantly associated with elevation of IOP. However, the results showed the stronger association of IOP with WC than BMI, whether they were adjusted by age and sex or additionally lifestyle variables. Conclusions: These data showed that BMI and WC were positively associated with IOP. However, WC appeared to be a better indicator for higher IOP than BMI.

키워드

참고문헌

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