DOI QR코드

DOI QR Code

THE RELATIONSHIP OF RADIOGRAPHIC LESION SIZE AND CHARACTERISTICS TO DIAGNOSIS OF PERIAPICAL CYSTS AND GRANULOMAS

방사선학적 치근단병소의 크기와 특징에 대한 치근단낭종 및 육아종의 상관관계연구

  • Choi, Ho-Sik (Department of Conservative Dentistry, School of Dentistry, Seoul National University) ;
  • Lee, Woo-Cheol (Department of Conservative Dentistry, School of Dentistry, Seoul National University) ;
  • Shon, Won-Jun (Department of Conservative Dentistry, School of Dentistry, Seoul National University) ;
  • Kum, Kee-Yeon (Department of Conservative Dentistry, School of Dentistry, Seoul National University) ;
  • Bae, Kwang-Shik (Department of Conservative Dentistry, School of Dentistry, Seoul National University) ;
  • Baek, Seung-Ho (Department of Conservative Dentistry, School of Dentistry, Seoul National University)
  • 최호식 (서울대학교 치의학대학원 치과보존학교실) ;
  • 이우철 (서울대학교 치의학대학원 치과보존학교실) ;
  • 손원준 (서울대학교 치의학대학원 치과보존학교실) ;
  • 금기연 (서울대학교 치의학대학원 치과보존학교실) ;
  • 배광식 (서울대학교 치의학대학원 치과보존학교실) ;
  • 백승호 (서울대학교 치의학대학원 치과보존학교실)
  • Published : 2010.01.29

Abstract

The purpose of this study was to find out the relationship of radiographic lesion size, gender, age of patients and radiographic character to the diagnosis of periapical cyst and granuloma. The data was collected from 187 periapical lesions of 167 patients who undergone apical surgery at Department of Conservative Dentistry, Seoul National University Dental Hospital from 2003 to 2005. The lesion were surgically removed and send for biopsy to the Oral Pathology Laboratory. From the initial radiograph, lesion size was calculated using $PiViewSTAR^{(R)}$ (INFINITT, Korea) program. The obtained data were statistically evaluated using SPSS (p<0.05). The result were as followings: 1. From 187 biopsy samples, the incidence of periapical cyst was 28.34% and granuloma was 65.24%. 2. There was a significant correlation between periapical cyst and the size of radiographic lesion (p<0.01). 3. There were no significant correlations between age, gender, location of lesion and the final diagnosis (p>0.05). 4. There was a significant correlation between the non-demarcation of the lesion and the incidence of periapical granuloma (p<0.01).

본 연구는 2003년부터 2005년까지 서울대학교 치과병원 보존과에 내원한 환자 중 치근단수술을 시행한 환자 167명에서 생검을 위해 적출한 187개의 치근단병소를 대상으로 하였다. 수술 후 조직검사 결과 얻은 진단명과 환자의 진단기록에서 환자의 성별, 나이, 발병 부위, 방사선 사진 상의 특징 그리고 병소의 크기와의 상관관계를 조사하였다. 초진시 방사선 사진에서 치근단병소의 크기를 $PiViewSTAR^{(R)}$ (INFINITT, Korea)를 이용하여 화소를 계산함으로써 면적을 구하였다. 이를 바탕으로 통계 분석프로그램 SPSS (version 12.0K, SPSS Inc., Chicago, IL, USA)를 이용해 방사선사진상 크기와 진단명과의 상관관계를 조사하였다. 나이와 진단명과의 상관관계는 일원배치 분산분석을 시행하고 성별, 부위, 방사선사진상의 특징과 진단명과의 상관관계는 교차분석을 통해 카이제곱검정으로 조사하여 다음과 같은 결론을 얻었다. 1. 187의 치근단병소 조직검사결과 치근단병소 중 치근단낭종의 비율은 28.34%, 육아종의 비율은 65.24%, 기타병소의 비율은 6.42%로 나타났다. 2. 방사선사진상 병소의 크기가 커질수록 치근단 낭종일 확률이 높았다(p<0.01). 3. 나이, 성별, 발병부위와 진단명사이에서 유의 한 상관관계가 없었다(p>0.05). 4. 병소의 경계가 명확하지 않은 것과 치근단육아종의 발생빈도는 통계적으로 유의한 상관관계를 보였다(p<0.01).

Keywords

References

  1. Natkin E, Oswald RJ, Carnes LI. The relationship of lesion size to diagnosis, incidence, and treatment of periapical cysts and granulomas, Oral Surg 57: 82-93, 1984. https://doi.org/10.1016/0030-4220(84)90267-6
  2. Nair PNR. New perspectives on radicular cysts: do they heal-, Int Endod J 31: 155-160, 1998, https://doi.org/10.1046/j.1365-2591.1998.00146.x
  3. Bhaskar SN. Nonsurgical resolution of radicular cysts. Oral Surg 34:458-468, 1972. https://doi.org/10.1016/0030-4220(72)90325-8
  4. Malassez ML. Sur l' existence de masses epitheliales dans le ligament alveolodentaire chez l' homme adulte et a l' etat normal. Com Rend Soc Biol 36:241-244, 1884.
  5. Torabinejad M, Kettering J. Identification and relative concentration of Band T lymphocytes in human chronic periapical lesions, J Endod 11:122-125, 1985. https://doi.org/10.1016/S0099-2399(85)80230-2
  6. Bohne W. Light and ultrastructural studies on human chronic periapical lesions. J Oral Pathol Med 19:215-20, 1990. https://doi.org/10.1111/j.1600-0714.1990.tb00828.x
  7. 조수진, 윤태철, 박동수. 치근단병소에서 면역글로불린의 분포에 관한 연구. 대한치과보존학회지 20:55-70, 1995.
  8. 백승호, 임성삼. 실험적 백서 치수 및 치근단 병소에서의 면역글로불린 G 아강분포에 관한 면역조직화학적 연구. 대한치과보존학회지 16:41-59, 1991.
  9. 부정선, 임성삼. 실험적 백서 치근단 병소에서의 면역글로불린 분포에 관한 면역조직화학적 연구. 대한치과보존학회지 15:58-75, 1990.
  10. Langeland K. Block RM. Grossman LI. A histopathologic and histobacteriologic study of 35 periapical endodontic surgical specimens. J Endod 3:8-23, 1977. https://doi.org/10.1016/S0099-2399(77)80217-3
  11. Yanagisawa S. Pathologic study of periapical lesions 1. Periapical granulomas: clinical. histopathologic and immunohistopathologic studies. J Oral Pathol Med 9: 288-300. 1980. https://doi.org/10.1111/j.1600-0714.1980.tb00386.x
  12. Skaug N, Nilsen R, Matre R, Bernhoff CH, Johannessen AC. In situ characterization of cell infiltrates in human dental periapieal granulomas. J Oral Pathol Med 11:47-57. 1982. https://doi.org/10.1111/j.1600-0714.1982.tb00142.x
  13. McCall JO. Wald SS. Clinical Dental Roentgenology, 3rd ed., WB Saunders Co., Philadelphia. PA. p192, 1952.
  14. Lalonde ER. A new rationale for management of periapical granulomas and cysts. An evaluation of histopathological and radiographic findings. J Am Dent Asso 80:1056-1059, 1970. https://doi.org/10.14219/jada.archive.1970.0236
  15. Sommer RF, Ostrander FD, Crowley MC. Clinical Endodontics. 1st ed., WB Saunders Co., Philadelphia, PA. p424-426, 1956.
  16. Bhaskar SN. Periapical lesions-types, incidence and clinical features. Oral Surg 21:657-671, 1966. https://doi.org/10.1016/0030-4220(66)90044-2
  17. Forsberg A. Hagglund F. Diffrential diagnosis of radicular cyst and granuloma: Use of X-ray contrast medium. Dent Radiogra Photogr 33:84-88, 1960.
  18. Toller PA. Protein substances in odontogenic cyst fluids. Br Dent J 128: 317-322, 1970. https://doi.org/10.1038/sj.bdj.4802465
  19. Morse DR, Patnik JW, Schacterle GR. Electrophoretic diffrentiation of radicular cyst and granulomas. Oral Surg 35:249-264, 1973. https://doi.org/10.1016/0030-4220(73)90292-2
  20. Morse DR, Schacterle GR, Wolfson EM. A rapid chairside diffrentiation of radicular cysts and granulomas. J Endod 2:17-20, 1976. https://doi.org/10.1016/S0099-2399(76)80026-X
  21. Grossmann LI, Root Canal Therapy, 3rd ed., Lea & Febiger, Philadelphia. PA. p.99, 1950.
  22. Baumann L, Rossmann SR. Clinical roentgenologic and histopathologic findings in teeth with apical radiolucent areas. Oral Surg 9:1330-1336, 1956. https://doi.org/10.1016/0030-4220(56)90235-3
  23. Linenberg WB, Waldron CA, De Laune GF Jr. A clinical. roentgenographic and histopathologic evaluation of periapical lesions. Oral Surg 17:467-472, 1964. https://doi.org/10.1016/0030-4220(64)90040-4
  24. Patterson SS, Shafer WG, Healey HJ. Periapical lesions associated with endodontically treated teeth. J Am Dent Asso 68:191-194, 1964. https://doi.org/10.14219/jada.archive.1964.0056
  25. Block RM, Bushell A, Rodrigues H, Langeland K. A histopathological, histobacteriologic and radiographic study of periapical endodontic surgical specimens. Oral Surg 42:656-678, 1976. https://doi.org/10.1016/0030-4220(76)90217-6
  26. Stafne EC. Oral roentgenographic and direct observation of experimental lesions in bone. J Am Dent Asso 62:708-716, 1961. https://doi.org/10.14219/jada.archive.1961.0127
  27. Sommer R. Clinical evaluation of diagnostic aids. D. Radiog. and Patholog. 27:17, 1954.
  28. Preibe WA, Lazansky JP, Wuehrmann AH. The Value of the roentgenographic film in the diffrential diagnosis of periapical lesions. Oral Surg 7:979-983, 1954. https://doi.org/10.1016/0030-4220(54)90297-2