Associated Factors with Severity of Atopic Dermatitis in Children

영유아의 아토피피부염 중증도 관련 요인 연구

  • Lee, Jae-Sun (Department of Nutrition counseling, Healthcare Center, Konkuk University Medical Center) ;
  • Jo, Sun-Mi (Department of Foods and Nutrition, Kookmin University) ;
  • Lee, Hee-Chul (Department of Pediatrics, Cheil General Hospital, Kwandong University College of Medicine) ;
  • Ahn, Kang-Mo (Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Chung, Sang-Jin (Department of Foods and Nutrition, Kookmin University)
  • 이재선 (건국대학교병원 헬스케어센터) ;
  • 조선미 (국민대학교 식품영양학과) ;
  • 이희철 (관동대학교 의과대학 제일병원 소아과) ;
  • 안강모 (성균관대학교 의과대학 삼성서울병원 소아과) ;
  • 정상진 (국민대학교 식품영양학과)
  • Received : 2010.11.10
  • Accepted : 2010.12.06
  • Published : 2010.12.31

Abstract

The prevalence of atopic dermatitis (AD) has increased over the past decades. A variety of factors are related to the development of atopic dermatitis, including genetics and environmental factors. The purpose of the study was to examine factors associated with severity of atopic dermatitis in 104 children aged 6-60 months. To investigate the association between severity and other factors children were divided into two groups, mild (n = 62) and severe (n = 42) groups, based on SCORAD index which measures the severity of atopic dermatitis. Results showed that family history, family's smoking, period of having AD and the levels of the serum total IgE were significantly higher in severe group. More than 6 months of breastfeeding and weaning after 6 month were not associated with severity of AD, but the number of food eliminated was associated with severity. Only vitamin C intake was significantly different by severity after adjusting for energy intake, family history, family’s smoking and period of having AD (p = 0.033). There was no association between the severity of atopic dermatitis and growth of children. This study concluded that the severity of atopic dermatitis was associated with family history, family’s smoking, period of having AD, children's serum total IgE, and vitamin C intakes. The result of this study should provide the significant information for better management of AD.

Keywords

References

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