생약학회지 (Korean Journal of Pharmacognosy)

  • 제41권4호
  • /
  • Pages.319-322
  • /
  • 2010
  • /
  • 0253-3073(pISSN)
  • /
  • 2288-9299(eISSN)
한국생약학회 (The Korean Society of Pharmacognosy)
권호 표지

전칠삼의 연근별 부위별 인삼 사포닌 함량 비교

The Comparison of Ginsenoside Composition Contents in Notoginseng Radix (Sanchi) on Various Parts and Ages

  • 이선아 (세명대학교 한방식품영양학부) ;
  • 유정 (중앙대학교 약학대학) ;
  • 조희경 (세명대학교 한방식품영양학부) ;
  • 임병옥 (세명대학교 자연약재과학과) ;
  • 조순현 ((주) 휴메딕스 중앙연구소) ;
  • 황완균 (중앙대학교 약학대학) ;
  • 고성권 (세명대학교 한방식품영양학부)
  • Lee, Sun-A (The Department of Oriental Medical Food & Nutrition, Semyung University) ;
  • Liuting, Liuting (College of Pharmacy, Chung-Ang University) ;
  • Jo, Hee-Kyung (The Department of Oriental Medical Food & Nutrition, Semyung University) ;
  • Im, Byung-Ok (The Department of Natural Medicine Resources, Semyung University) ;
  • Cho, Soon-Hyun (Central Research Institute, Humedix Co. Ltd.) ;
  • Whang, Wan-Kyun (College of Pharmacy, Chung-Ang University) ;
  • Ko, Sung-Kwon (The Department of Oriental Medical Food & Nutrition, Semyung University)
  • 투고 : 2010.09.03
  • 심사 : 2010.12.06
  • 발행 : 2011.12.31
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

This study was to obtain essential information that can be used to index Notoginseng Radix(Panax notoginseng, Sanchi) cultivated in Winnan, China. The ginsenoside contents in various Sanchi on various parts and ages were quantitatively analyzed by HPLC. The average of total saponin and the ginsenoside contents of each 3-year-old Sanchi cultivated in China were higher than those of the Sanchi for longer period. As a result, the order of the total saponin contents was 3-year-old (7.13%), 4-year-old (6.27%), 5-year-old (5.34%), and 6-year-old (4.06%) Sanchi. On the other hand, the total saponin average and the ginsenoside contents of each of the fine roots, lateral roots, and rhizomes of Sanchi cultivated in China were similar to the 6-year-old Sanchi.

키워드

참고문헌

  1. Ko, S. K. and Im, B. O. (2009) The Science of Korean ginseng, 118-129. Yakupsinmun, Seoul.
  2. Wakabayashi, C., Hasegawa, H., Murata, J. and Saiki, I. (1997) In vivo antimetastatic action of ginseng protopanaxadiol saponins is based on their intestinal bacterial metabolites after oral administration. Oncol. Res. 98: 411-417.
  3. Xie, J. T., Aung, H. H., Wang, C. Z., Mehendale, S. R., McEntee, Eryn., Wicks, Sheila., Li, Jing. and Yuan, C. Su. (2006) Effects of Panax notoginseng, ginsenoside $Rb_{1}$, and notoginsenoside $R_{1}$ on proliferation of human breast carcinoma MCF-7 cells. Orient Pharm. Exp. Med. 6: 286-292. https://doi.org/10.3742/OPEM.2006.6.4.286
  4. Robbie, Y. K., Chan, W. F., Chen, A. D., Dean, G. and Man, S. W. (2002) Estrogen-Like Activity of Ginsenoside $Rg_{1}$ Derived from Panax notoginseng. J. Clin. Endocrinol. Metabo. 87: 3691-3695. https://doi.org/10.1210/jc.87.8.3691
  5. Park. S. K., Ju, S. T,, Ban, C. K., Moon, J. Y., Park, S. D. and Park, W. H. (2006) Inhibitory Effect of Panax notoginseng on Nitric Oxide Synthase, Cyclo-oxygenase-2 and Neutrophil Functions. Korean J. Oriental. Physiology & Pathology. 20: 1295-1302.
  6. Shin, J. C., Moon, J. Y. and Park, W. H. (2006) Inhibitory effect of Panax notoginseng and emodin on LPS-induced iNOS, COX-2 and prostaglandin E2. Korean J. Oriental. Physiology & Pathology 20: 724-729.
  7. Park, Y. K. and Jung, H. W. (2006) Original Articles : Panax notoginseng inhibits LPS-induced pro-inflammatory mediators in microglia. The Korea Association of Herbology 21: 93-101.
  8. Choi, K. J., Kim, M. W. and Lee, J. S. (1982) Comparative studies on the Chemical Components in Ginseng - 1. The ginsenosides and the free sugars content of various ginseng plants. korean J. Ginseng Sci. 6: 138-142.
  9. Bai, C., Chai, X., Gao, X., Li, P. and Tu, P. (2009) HPLCCAD in optimization of saponins extraction from Radix et Rhizoma Notoginseng. Zhongguo Zhong Yao Za Zhi 34: 677-680.
  10. Choi, K. J., Kim, M. W., Ko, S. R. and Kim, S. C. (1987) Distribution of Saponin in Various Sections of Panax ginseng root and Changes of Its Contents According to Root Age. korean J. Ginseng Sci. 11: 10-17.
  11. Namba, T., Yoshizaki, M., Tomimori, T., Kobashi, K. and Mitsui, K. (1974) Chemical and biochemical evaluation of ginseng and related crude drugs. Yakugaku Zasshi 94: 252-260. https://doi.org/10.1248/yakushi1947.94.2_252
  12. Lee, C. R., Whang, W. K., Shin, C. G., Lee, H. S., Han, S. T., Im, B. O. and Ko, S. K. (2004) Comparison of ginsenoside composition and contents in fresh ginseng roots cultivated in Korea, japan, and China at various ages. Korean J. Food Sci. Technol. 36: 847-850.
  13. Shibata, S., Tanaka, T., Ando, T., Sado, M., Tsushima, S. and Ohsawa, T. (1966) Chemial Studies on oriental plant drugs (XIV) Prtopanaxadiol, a genuine sapogenin of ginseng saponins. Chem. Pharm. Bull. 14: 595-600. https://doi.org/10.1248/cpb.14.595
  14. Ko, S. K., Bae, H. M., Cho, O. S., Im, B. O., Chung, S. H. and Lee, B. Y. (2008) Analysis of ginsenoside composition of ginseng berry and seed. Food Sci. Biotechnol. 17: 1379-1382.
  15. Park, J. D. (1996) Recent studies on the chemical constituents of Korean ginseng (Panax ginseng C.A. Meyer). Korean J. Ginseng Sci. 20: 389-415.