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다발성 유아기 흑색 신경외배엽성 종양의 치험례

Multicentric melanotic neuroectodermal tumor of infancy: a case report

  • 최병환 (울산대학교 의과대학 구강악안면외과학교실) ;
  • 박수원 (울산대학교 의과대학 구강악안면외과학교실) ;
  • 장수미 (울산대학교 의과대학 구강악안면외과학교실) ;
  • 박봉찬 (울산대학교 의과대학 구강악안면외과학교실) ;
  • 손한나 (울산대학교 의과대학 구강악안면외과학교실) ;
  • 손장호 (울산대학교 의과대학 구강악안면외과학교실) ;
  • 성일용 (울산대학교 의과대학 구강악안면외과학교실) ;
  • 김종렬 (온병원 구강악안면외과) ;
  • 조영철 (울산대학교 의과대학 구강악안면외과학교실)
  • Choi, Byoung-Hwan (Department of Oral and Maxillofacial Surgery, College of Medicine, University of Ulsan) ;
  • Park, Su-Won (Department of Oral and Maxillofacial Surgery, College of Medicine, University of Ulsan) ;
  • Jang, Soo-Mi (Department of Oral and Maxillofacial Surgery, College of Medicine, University of Ulsan) ;
  • Park, Bong-Chan (Department of Oral and Maxillofacial Surgery, College of Medicine, University of Ulsan) ;
  • Son, Han-Na (Department of Oral and Maxillofacial Surgery, College of Medicine, University of Ulsan) ;
  • Son, Jang-Ho (Department of Oral and Maxillofacial Surgery, College of Medicine, University of Ulsan) ;
  • Sung, Iel-Yong (Department of Oral and Maxillofacial Surgery, College of Medicine, University of Ulsan) ;
  • Kim, Jong-Ryoul (Department of Oral and Maxillofacial Surgery, Onhospital) ;
  • Cho, Yeong-Cheol (Department of Oral and Maxillofacial Surgery, College of Medicine, University of Ulsan)
  • 투고 : 2010.07.14
  • 심사 : 2010.10.22
  • 발행 : 2010.10.29

초록

A melanotic neuroectodermal tumor of infancy (MNTI) is a uncommon osteolytic pigmented neoplasm that primarily affects the jaws of newborn infants. Most patients (> 90%) present with the tumor in the first year of life. Approximately 65% form in the maxilla, 11% in the mandible, 5% in the brain and elsewhere. MNTI is normally benign, but up to 15% may recur and a few have metastasized. Approximately 200 cases of MNTI have been reported but only 2 of them presented as multifocal. A case of MNTI in a 7 month old boy was encountered. The chief complaint was maxillary anterior ridge swelling. The incisional biopsy findings were MNTI. Two months after the first operation, mild swelling of another site was observed. The infant was examined periodically since undergoing two procedures with no recurrence. This case demonstrates the possibility of a multicentric MNTI. We report a multicentric MNTI with a review of the relevant literature.

키워드

참고문헌

  1. Johnson RE, Scheithauer BW, Dahlin DC. Melanotic neuroectodermal tumor of infancy. A review of seven cases. Cancer 1983; 52:661-6. https://doi.org/10.1002/1097-0142(19830815)52:4<661::AID-CNCR2820520416>3.0.CO;2-X
  2. Lopez J Jr. Melanotic neuroectodermal tumor of infancy: review of the literature and report of a case. J Am Dent Assoc 1976;93: 1159-64..
  3. Krompecher E. Zur Histogenese und Morphologie der Adamantinome und sonstiger Kiefergeschwulste. Beitr Pathol Anat Allg Pathol 1918;64:165-97.
  4. Borello ED, Gorlin RJ. Melanotic neuroectodermal tumor of infancy- a neoplasm of neural crese origin. Report of a case associated with high urinary excretion of vanilmandelic acid. Cancer 1966;19:196-206. https://doi.org/10.1002/1097-0142(196602)19:2<196::AID-CNCR2820190210>3.0.CO;2-6
  5. Koudstaal J, Oldhoff J, Panders AK, Hardonk MJ. Melanotic neuroectodermal tumor of infancy. Cancer 1968;22:151-61. https://doi.org/10.1002/1097-0142(196807)22:1<151::AID-CNCR2820220118>3.0.CO;2-3
  6. Lee CH, Hong SP, Lim CY, Chi JG. Melanotic neuroectodermal tumor of infancy. J Korean Med Sci 1986;1:63-7.
  7. Navas palacios JJ. Malignant melanotic neuroectodermal tumor: light and electron microscopic study. Cancer 1980;46:529-36. https://doi.org/10.1002/1097-0142(19800801)46:3<529::AID-CNCR2820460318>3.0.CO;2-4
  8. Stowens D, Lin TH. Melanotic progonoma of the brain. Hum Pathol 1974;5:105-13. https://doi.org/10.1016/S0046-8177(74)80104-8
  9. Block JC, Waite DE, Dehner LP, Leonard AS, Ogle RG, Gatto DJ. Pigmented neuroectodermal tumor of infancy. An example of rarely expressed malignant behavior. Oral Surg Oral Med Oral Pathol 1980;49:279-85. https://doi.org/10.1016/0030-4220(80)90133-4
  10. Oruckaptan HH, Soylemezoglu F, Kutluk T, Akalan N. Benign melanotic tumor in infancy: discussion on a rare case and review of the literature. Pediatr Neurosurg 2000;32:240-7. https://doi.org/10.1159/000028945
  11. Cawson RA, Binnie WH, Barret AW, Wright JM, eds. Oral disease. 3rd ed. London: Mosby; 2001.
  12. Steinberg B, Shuler C, Wilson S. Melanotic neuroectodermal tumor of infancy: evidency for multicentricity. Oral Surg Oral Med Oral Pathol 1988;66:666-9. https://doi.org/10.1016/0030-4220(88)90314-3
  13. Jones P, Williams A. A case of multicentric melanotic adamantinomata. Br J Surg 1960;48:282-5. https://doi.org/10.1002/bjs.18004820908
  14. Nagase M, Ueda K, Fukushima M, Nakajima T. Recurrent melanotic neuroectodermal tumour of infancy. Case report and survey of 16 cases. J Maxillofac Surg 1983;11:131-6. https://doi.org/10.1016/S0301-0503(83)80032-0
  15. Puchalski R, Shah UK, Carpentieri D, McLaughlin R, Handler SD. Melanotic neuroectodermal tumor of infancy (MNTI) of the hard palate: presentation and management. Int J Pediatr Otorhinolaryngol 2000;53:163-8. https://doi.org/10.1016/S0165-5876(00)00315-3
  16. Hoshina Y, Hamamoto Y, Suzuki I, Nakajima T, Ida-Yonemochi H, Saku T. Melanotic neuroectodermal tumor of infancy in the mandible: report of a case. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2000;89:594-9. https://doi.org/10.1067/moe.2000.105519
  17. Mosby EL, Lowe MW, Cobb CM, Ennis RL. Melanotic neuroectodermal tumor of infancy: review of the literature and report of a case. J Oral Maxillofac Surg 1992;50:886-94. https://doi.org/10.1016/0278-2391(92)90285-8
  18. Slootweg PJ. Heterologus tissue elements in melanotic neuroectodermal tumor of infancy. J Oral Pathol Med 1992;21:90-2. https://doi.org/10.1111/j.1600-0714.1992.tb00986.x

피인용 문헌

  1. Melanotic neuroectodermal tumour of infancy: Report of two cases and review of the literature vol.40, pp.4, 2010, https://doi.org/10.1016/j.jcms.2011.05.013