Neonatal Medicine

  • 제17권2호
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  • Pages.168-180
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  • 2010
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  • 2287-9412(pISSN)
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  • 2287-9803(eISSN)
대한신생아학회 (The Korean Society of Neonatology)
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신생아 급성 신부전의 치료

Treatment of Acute Renal Failure in Neonate

  • 이진아 (서울대학교 의과대학 소아과학교실)
  • Lee, Jin-A (Division of Neonatology, Department of Pediatrics, Seoul National University College of Medicine)
  • 발행 : 2010.11.30
⟨ 이전 논문 다음 논문 ⟩

초록

Acute renal failure (ARF) is common in the neonatal period, however, there are no uniform treatment strategies of ARF. The main treatment strategies are conservative management including medical treatment and the renal replacement therapy. Because ARF in the newborn is commonly acquired by hypoxic ischemic injury and toxic insults, removal of all the offending causes is important. Aminoglycoside, indomethacin, and amphotericin-B are the most common nephrotoxic drugs of ARF. To relieve the possible prerenal ARF, initial fluid challenge can be followed by diuretics. If there is no response, fluid restriction and correction of electrolyte imbalance should begin. Adequate nutritional support and drug dosing according to the pharmacokinetics of such drugs will be difficult problems. Renal replacement therapies may be provided by peritoneal dialysis, intermittent hemodialysis, or hemofiltration. New promising agents, bioartificial kidney, and stem cell will enable us to extend our therapeutic repertoire.

키워드

참고문헌

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피인용 문헌

  1. Antimicrobial Management of Neonatal Sepsis vol.19, pp.2, 2010, https://doi.org/10.5385/jksn.2012.19.2.53
  2. Continuous Renal Replacement Therapy in the Neonatal Intensive Care Unit: A Single-Center Study vol.21, pp.4, 2010, https://doi.org/10.5385/nm.2014.21.4.244