Natural Product Sciences

The Korean Society of Pharmacognosy (한국생약학회)
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Inhibition of Aldose Reductase from Rat Lenses by Methanol Extracts from Korean Folk Plants

  • Kim, Hye-Min (Department of Applied Plant Science, Chung-Ang University) ;
  • Mok, So-Youn (Department of Applied Plant Science, Chung-Ang University) ;
  • Lee, Jeong-Min (Department of Applied Plant Science, Chung-Ang University) ;
  • Cho, Eun-Ju (Department of Food Science and Nutrition, Pusan National University) ;
  • Choi, Kyung (Department of Forest Resource Conservation, Korea National Arboretum) ;
  • Ku, Ja-Jung (Department of Forest Resource Conservation, Korea National Arboretum) ;
  • Park, Kwang-Woo (Department of Forest Resource Conservation, Korea National Arboretum) ;
  • Lee, Sang-Hyun (Department of Applied Plant Science, Chung-Ang University)
  • Received : 2010.10.13
  • Accepted : 2010.11.25
  • Published : 2010.12.31
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Abstract

The inhibition of rat lens aldose reductase (AR) in vitro using methanol extracts from Korean folk plants was investigated. Among them, the extracts of Saussurea grandifolia and Rumex crispus showed highest inhibition of AR. $IC_{50}$ values of the extracts from S. grandifolia and R. crispus were demonstrated 0.07 and 0.05 mg/ml, respectively. Korean folk plants such as S. grandifolia and R. crispus has a possibility of new natural resources for the inhibition of AR.

Keywords

References

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