사상체질의학회지 (Journal of Sasang Constitutional Medicine)

  • 제21권3호
  • /
  • Pages.209-215
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  • 2009
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  • 1226-4075(pISSN)
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  • 2287-786X(eISSN)
사상체질의학회 (The Society Of Sasang Constitutional Medicine)
권호 표지

열다한소탕가대황(熱多寒少湯加大黃) 복용 후 간 손상 수치가 상승된 1례

A Clinical Case of Liver Injury with Administration of Yeoldahanso-tang plus Rheum rhabarbarum

  • 권은미 (경희대학교 동서신의학병원 사상체질과) ;
  • 정의홍 (경희대학교 동서신의학병원 사상체질과) ;
  • 김은희 (경희대학교 동서신의학병원 사상체질과) ;
  • 서영광 (경희대학교 동서신의학병원 사상체질과) ;
  • 이수경 (경희대학교 동서신의학병원 사상체질과) ;
  • 김달래 (경희대학교 동서신의학병원 사상체질과) ;
  • 김선형 (경희대학교 동서신의학병원 사상체질과)
  • Kwon, Eun-Mi (Dept. of Sasang Constitutional Medicine, Kyunghee University East-West Neo Medical Center) ;
  • Jung, Yee-Hong (Dept. of Sasang Constitutional Medicine, Kyunghee University East-West Neo Medical Center) ;
  • Kim, Eun-Hee (Dept. of Sasang Constitutional Medicine, Kyunghee University East-West Neo Medical Center) ;
  • Seo, Young-Kwang (Dept. of Sasang Constitutional Medicine, Kyunghee University East-West Neo Medical Center) ;
  • Lee, Soo-Kyung (Dept. of Sasang Constitutional Medicine, Kyunghee University East-West Neo Medical Center) ;
  • Kim, Dal-Rae (Dept. of Sasang Constitutional Medicine, Kyunghee University East-West Neo Medical Center) ;
  • Kim, Sun-Hyung (Dept. of Sasang Constitutional Medicine, Kyunghee University East-West Neo Medical Center)
  • 투고 : 2009.06.20
  • 심사 : 2009.12.02
  • 발행 : 2009.12.31
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초록

1. Objects: This case study reports a liver injury in treatment of constipation with Yeoldahanso-tang plus Rheum rhabarbarum. 2. Methods: The patient's subjective symptoms and the laboratory data including aspartate transaminase(AST), alanine transaminase(ALT), alkaline phosphatase(ALP), and gamma($\gamma$)-glutamyl transpeptidase(GGT) were observed before and after liver injury. We used the Roussel Uclaf Causality Assessment Method(RUCAM) scale in order to find out whether if Yeoldahanso-tang plus Rheum rhabarbarum was related with the liver injury. 3. Results: The patient's AST and ALT were elevated more than twice after a 3week administration period of herbal medicine. After discontinuation of the herbal medicine and administration of hepatic protective medication, AST and ALT decreased. The patient's general condition improved during hospitalization. The RUCAM score was estimated at 8. 4. Conclusions: This case is presented to bring more attention to the toxicity of herbal medicine.

키워드

참고문헌

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