Journal of Korean Dental Science

Korean Academy of Dental Science (대한치의학회)
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Cytotoxicity of Root Canal Sealers Containing Calcium Hydroxide

  • Kim, In-Geol (HanYang Dental Clinic/dbchemTM in Namyangju City) ;
  • Han, Se-Hee (Department of Conservative Dentistry, Medical center for Joong Ang University) ;
  • Cho, Young-Gon (Department of Conservative Dentistry, School of Dentistry, Chosun University) ;
  • Lee, Sang-Bae (Department and Research Institute of Dental Biomaterials and Bioengineering, College of Dentistry, Yonsei University) ;
  • Kim, Kwang-Mahn (Department and Research Institute of Dental Biomaterials and Bioengineering, College of Dentistry, Yonsei University) ;
  • Kim, Kyoung-Nam (Department and Research Institute of Dental Biomaterials and Bioengineering, College of Dentistry, Yonsei University)
  • Published : 2009.06.30
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Abstract

The purpose of this study was to investigate the possibility to reduce the toxicity of oil based root canal sealers containing calcium hydroxide using MTT & agar overlay assays. Thus some formulations of traditional root canal sealers were replaced with oil-soluble solvents and experimental root canal sealers manufactured. In MTT assay, Cell viability of all experimental sealers in addition with oil soluble solvents were observed significantly higher than both control groups, especially according to replace zinc and/or calcium ion components. Also agar overlay assay was appeared moderate to no cell responses into modifying both zinc and/or calcium ion components and oil soluble solvent weight. Authors found the reducing effect of cell toxicity through significant role of oil soluble solvent factor into root canal sealer containing calcium hydroxide.

Keywords

References

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