한국임상수의학회지 (Journal of Veterinary Clinics)

  • 제26권3호
  • /
  • Pages.263-267
  • /
  • 2009
  • /
  • 1598-298X(pISSN)
  • /
  • 2384-0749(eISSN)
한국임상수의학회 (The Korean Society of Veterinary Clinics)
권호 표지

개 다발성 림프종에 대한 Lomustine 및 Prednisolone을 이용한 Low-budget protocol 적용 증례

Application of Low-Budget Protocol with Lomustine and Prednisolone for Multicentric Lymphoma in a Dog

  • 이도형 (충남대학교 동물의과학연구소, 수의과대학) ;
  • 임수정 (충남대학교 동물의과학연구소, 수의과대학) ;
  • 손선호 (충남대학교 동물의과학연구소, 수의과대학) ;
  • 이선희 (충남대학교 동물의과학연구소, 수의과대학) ;
  • 전형규 (충남대학교 동물의과학연구소, 수의과대학) ;
  • 최호정 (충남대학교 동물의과학연구소, 수의과대학) ;
  • 이영원 (충남대학교 동물의과학연구소, 수의과대학) ;
  • 조성환 (충남대학교 동물의과학연구소, 수의과대학) ;
  • 송근호 (충남대학교 동물의과학연구소, 수의과대학)
  • Lee, Do-Hyung (Research Institute of Veterinary Medicine and College of Veterinary Medicine, Chungnam National University) ;
  • Lim, Soo-Jung (Research Institute of Veterinary Medicine and College of Veterinary Medicine, Chungnam National University) ;
  • Son, Sun-Ho (Research Institute of Veterinary Medicine and College of Veterinary Medicine, Chungnam National University) ;
  • Lee, Sun-Hee (Research Institute of Veterinary Medicine and College of Veterinary Medicine, Chungnam National University) ;
  • Jun, Hyung-Kyou (Research Institute of Veterinary Medicine and College of Veterinary Medicine, Chungnam National University) ;
  • Choi, Ho-Jung (Research Institute of Veterinary Medicine and College of Veterinary Medicine, Chungnam National University) ;
  • Lee, Young-Won (Research Institute of Veterinary Medicine and College of Veterinary Medicine, Chungnam National University) ;
  • Cho, Sung-Whan (Research Institute of Veterinary Medicine and College of Veterinary Medicine, Chungnam National University) ;
  • Song, Kun-Ho (Research Institute of Veterinary Medicine and College of Veterinary Medicine, Chungnam National University)
  • 발행 : 2009.06.30
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

A 9-year-old, female, Maltese Dog(2.15 kg of body weight) was referred to the Veterinary Medical Teaching Hospital, Chungnam National University with cervical masses, abdominal masses and petechia. Physical examination showed masses in mandibular, prescapular, inguinal, popliteal lymph node and abdominal subcutaneous hemorrhage. This case was diagnosed as the multicentric lymphoma by physical examination, laboratory examination, radiography, ultrasonography, CT, fine needle aspiration and histopathologic examination. This dog was treated by low-budget protocol with lomustine and prednisolone. The dog show that response duration and survival time is 143days and 263 days, respectively.

키워드

참고문헌

  1. Argyle DJ, Brearley MJ, Turek MM. Canine lymphoma and leukemia. In: Decision making in small animal oncology, 2008:171-209
  2. Ettinger SJ, Feldman EC. Hematopoietic tumors. In: Textbook of veterinary internal medicine, 6 ed. St Louis: Elsevier Saunders. 2005:732-741
  3. Kristal O, Rassnick K, Gliatto JM, Northrup NC, Chretin JD, Morrison-Collister K, Cotter SM, Moore AS. Hepatotoxicity associated with CCNU (lomustine) chemotherapy in dogs, J Vet Intern Med 2004;18:75-80
  4. Meyer DJ, Raskin RE. Lymphoma. In: Atlas of canine and feline cytology, St. Louis: WB Saunders Co. 2001:108-119
  5. Moore AS, Ogilvie GK, Ruslander D, Rand WS, Cotter SM, Getzy DM, L'Heureux DA, Dennis RA. Evaluation of mitoxantrone for the treatment of lymphosarcoma in dogs. J Am Vet Med Assoc 1994;205:1903-1905
  6. Myers NC 3rd, Moore AS, Rand WM, Gliatto J, Cotter SM. Evaluation of a multidrug chemotherapy protocol (ACOPAII) in dogs with lymphoma. J Vet Intern Med 1997;11:333-339 https://doi.org/10.1111/j.1939-1676.1997.tb00476.x
  7. Nelson RW, Couto CG. Lymphoma in the cat and dog. In: Small animal internal medicine, 3rd ed. St Louis: Mosby. 2003: 1122-1132
  8. Ogilvie GK, Moore AS. Lymphosarcoma. In: managing the veterinary cancer patient, Trenton: Veterinary Learning Systems. 1995:228-259
  9. Plumb DC. Doxorubicin. In: Veterinary drug handbook, 4th ed. Ames: Iowa State Press. 2002: 310-313
  10. Postorino NC, Susaneck SJ, Eithrow SJ. Single agent therapy with adriamycin for canine lymphosarcoma. J Am Anim Hosp Assoc 1989;25:221-225
  11. Sauerbrey ML, Mullins MN, Bannink EO, Van Dorp TE, Kaneene JB, Obradovich JE. Lomustine and prednisone as a first-line treatment for dogs with multicentric lymphoma: 17 cases (2004-2005) J Am Vet Med Assoc 2007;230:1866-1869 https://doi.org/10.2460/javma.230.12.1866
  12. Squire RA, Bush M, Melby EC, Neeley LM, Yarbrough B. Clinical and pathologic study of canine lymphoma: clinical staging, cell classification and therapy. J Natl Cancer Inst 1973;51:565-574
  13. Thrall DE. Abdomonal masses. In: Textbook of veterinary radiology, 4th ed. Newyork: Elsevier Inc. 2002:513-515
  14. Withrow SJ, Vail DM. Hematopoietic tumors. In: Small animal clinical oncology, 4th ed. St Louis: WB Saunders. 2007: 172-173