Korean Journal of Pharmacognosy (생약학회지)

The Korean Society of Pharmacognosy (한국생약학회)
권호 표지

Inhibitory Activity of Medicinal Plants against Differentiation of Osteoclasts

생약의 파골 세포 분화 저해활성 검색

  • Lee, Jun-Won (Department of Life Science and Genetic Engineering, Paichai University)
  • 이준원 (배재대학교 과학기술바이오대학 생명유전공학과)
  • Published : 2009.06.30
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Abstract

Bone is continuously remodeled by osteoblasts and osteoclasts. Osteoclasts play an important role in bone metabolism by resorbing the bone matrix. Thus, the compounds inhibiting osteoclasts can improve bone diseases such as osteoporosis. The methanol extracts of 159 herbal medicines were screened for the inhibitory activity against differentiation of osteoclasts. Among the tested extracts, Achuranthis Radix and Corydalis Tuber showed relatively strong inhibitory activity against differentiation of osteoclasts, whereas they have no significant effect on proliferation of osteoclasts.

Keywords

References

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