Journal of The Korean Society of Clinical Toxicology (대한임상독성학회지)
- Volume 7 Issue 1
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- Pages.23-25
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- 2009
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- 1738-1320(pISSN)
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- 2508-6332(eISSN)
A Case of Seizure in Diphenhydramine Overdose
디펜히드라민 음독 후 경기를 주소로 응급센터에 내원한 환자 1례
- Park, Jung-Soo (Department of Emergency Medicine,, College of Medicine, Chungbuk National University) ;
- Kim, Hoon (Department of Emergency Medicine,, College of Medicine, Chungbuk National University) ;
- Lee, Suk-Woo (Department of Emergency Medicine,, College of Medicine, Chungbuk National University)
- Published : 2009.06.12
Abstract
A 21-year-old woman ingested 1,250 mg of diphenhydramine in a single overdose. Diphenhydramine, a rare ingredient in over-the-counter medication, is used to treat insomnia in Korea. Toxicity is usually limited to anticholinergic symptoms. The standard approach to therapy for the treatment of diphenhydramine overdose is supportive care, including physostigmines and sodium bicarbonates. Here, we review the literature and for the first time report a case of acute diphenhydramine overdosage in Korea, complicated with seizures.