Maxillofacial Plastic and Reconstructive Surgery

  • 제31권1호
  • /
  • Pages.77-80
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  • 2009
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  • 2288-8101(pISSN)
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  • 2288-8586(eISSN)
대한악안면성형재건외과학회 (Korean Association of Maxillofacial Plastic and Reconstructive Surgeons)
권호 표지

구강 내에 발생한 원발성 점막관련 림프양 림프종의 치험례

PRIMARY EXTRANODAL MARGINAL ZONE B-CELL LYMPHOMA OF MUCOSA-ASSOCIATED LYMPHOID TISSUE IN THE ORAL CAVITY : A CASE REPORT

  • 손장호 (울산대학교 의과대학 울산대학교병원 구강악안면외과) ;
  • 박수원 (울산대학교 의과대학 울산대학교병원 구강악안면외과) ;
  • 최병환 (울산대학교 의과대학 울산대학교병원 구강악안면외과) ;
  • 조영철 (울산대학교 의과대학 울산대학교병원 구강악안면외과) ;
  • 성일용 (울산대학교 의과대학 울산대학교병원 구강악안면외과) ;
  • 변기정 (울산대학교 의과대학 울산대학교병원 구강악안면외과)
  • Son, Jang-Ho (Department of Oral and Maxillofacial Surgery, Ulsan University Hospital, Medical College of Ulsan University) ;
  • Park, Su-Won (Department of Oral and Maxillofacial Surgery, Ulsan University Hospital, Medical College of Ulsan University) ;
  • Choi, Byoung-Hwan (Department of Oral and Maxillofacial Surgery, Ulsan University Hospital, Medical College of Ulsan University) ;
  • Cho, Yeong-Cheol (Department of Oral and Maxillofacial Surgery, Ulsan University Hospital, Medical College of Ulsan University) ;
  • Sung, Iel-Young (Department of Oral and Maxillofacial Surgery, Ulsan University Hospital, Medical College of Ulsan University) ;
  • Byun, Ki-Jeong (Department of Oral and Maxillofacial Surgery, Ulsan University Hospital, Medical College of Ulsan University)
  • 발행 : 2009.01.31
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초록

Mucosa-associated lymphoid tissue(MALT) lymphoma is thought to originate from marginal zone B-cells. In the WHO classification, Extranodal marginal zone lymphoma of MALT is classified B-cell Non-Hodgkin lymphoma. Common sites of MALT lymphoma include stomach, lung and the ocular-adnexa. Although less common in other sites, it is the most common low-grade lymphoma of the breast, thyroid, bowel skin and soft tissue. No strong age or gender predominance exists in MALT lymphoma. Dissemination to other sites can occur. In the oral cavity, MALT lymphoma is rare. Herein, we present a case of intra-oral MALT lymphoma. 66 year-old woman without any background of immunodeficiency or autoimmune disease admitted department of oral & maxillofacial surgery in Ulsan university hospital for evaluation of long-standing mild upper lip swelling. The lesion was completely resected and biopsied. Histological and immunohistochemical stains(CD3, CD5, CD20, CD21, CK) findings were used to confirm the lesion. Bone marrow biopsy was done and no bone marrow involvement was found. She did not receive chemotherapy and radiotherapy after surgery. No recurrence has been noted in the 22 months to date.

키워드

참고문헌

  1. Isaacson PG: Mucosa-associated lymphoid tissue lymphoma. Semin Hematol 36: 139-147, 1999
  2. Mattew J, Andrew D: Overview of Lymphoma Diagnosis and Management. Radiologic clinics of North America 46(issue2), 2008 https://doi.org/10.1016/j.rcl.2008.03.005
  3. Thieblemont C, Berger F, Dumontet C et al: Mucosa-associated lymphoid tissue lymphoma is a disseminated disease in one third of 158 patients analyzed. Blood 95 : 802-806, 2000
  4. Harris N, Jaffe E, Stein H: A revised European-American classification of lymphoid neoplasms: a proposal from the International Lymphoma Study Group. Blood 84 : 1631-1692, 1994
  5. Devita VT Jr., Hellman S, Rosenberg SA: Cancer. Principles and practice of oncology. 5th ed. New York, Lippincott-Raven, 2165-2197, 1997
  6. DePena CA, Van-Tassel P, Lee YY: Lymphoma of the head and neck. Radiol Clin North Am 28: 7223-43, 1990
  7. Eisenbud L, Sciubba J, Mir R et al: Oral presentation in Non-Hodgkin's lymphoma: a review of 31 cases. Part I. Data analysis. Oral Surg Oral Med Oral Pathol 56: 151-6, 1983 https://doi.org/10.1016/0030-4220(83)90281-5
  8. Jacobs C, Hoppe RT : Non-Hodgkin's lymphoma of the head and neck extranodal sites. Int J Radiat Oncol Biol Phys 11: 357-64, 1985 https://doi.org/10.1016/0360-3016(85)90158-0
  9. Solomides CC, Miller AS, Christmas RA et al: Lymphomas of the oral cavity: Histology, immunologic type, and inci-dence of Epstein-Barr virus infection. Hum Pathol 33: 153-7, 2002 https://doi.org/10.1053/hupa.2002.30721
  10. Sundeen JT, Longo DL, Jafffe ES: CD5 expression in Bcell lymphoma. Cancer 52: 1410-1416, 1983 https://doi.org/10.1002/1097-0142(19831015)52:8<1410::AID-CNCR2820520813>3.0.CO;2-3
  11. Joel BE, Joshua DE, Nhu DL: Characteristics of oral and paraoral malignant lymphoma: A population-based review of 361 cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 92: 519-25, 2001 https://doi.org/10.1067/moe.2001.116062
  12. Hanna E, Wanamaker J, Adelstein D et al: Extranodal lymphomas of the head and neck. A 20-year experience. Arch Otolaryngol Head Neck Surg 1318-23, 1997 https://doi.org/10.1001/archotol.1997.01900120068011
  13. Mill WB, Lee FA, Franssila KO: Radiation therapy treatment of stage I and II extranodal Non-Hodgkin's lymphoma of the head and neck. Cancer 653-61, 1980 https://doi.org/10.1002/1097-0142(19800215)45:4<653::AID-CNCR2820450406>3.0.CO;2-M
  14. Bragg DG: Radiology of the lymphomas. Curr Probl Diagn Radiol 16: 177-206, 1987 https://doi.org/10.1016/S0363-0188(87)80001-4
  15. Alkan S, Karcher DS, Newman MA et al: Regression of salivary gland MALT lymphoma after treatment for Helicobacter pylori. Lancet 348: 268-269, 1996
  16. Royer B, Cazals-Hatem D, Sibilla J et al: Lymphoma in patients with Sjogren's syndrome are marginal zone B-cell neoplasms, arise in diverse extranodal and nodal sites, and are not associated with viruses. Blood 90: 766-775, 1997
  17. Ioachim HL, Antonescu C, Giancotti F et al: EBV-associated primary lymphomas in the salivary glands of HIVinfected patients. Pathol Res. Pract 194: 87-95, 1998 https://doi.org/10.1016/S0344-0338(98)80075-7