Maxillofacial Plastic and Reconstructive Surgery

  • 제31권1호
  • /
  • Pages.71-76
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  • 2009
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  • 2288-8101(pISSN)
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  • 2288-8586(eISSN)
대한악안면성형재건외과학회 (Korean Association of Maxillofacial Plastic and Reconstructive Surgeons)
권호 표지

양성 및 악성 타액선 근상피종: 증례보고 및 면역조직화학적 연구

BENIGN AND MALIGNANT MYOEPITHELIOMAS IN SALIVARY GLAND: CASES REPORT AND IMMUNOHISTOCHEMICAL STUDY

  • 변준호 (경상대학교 의학전문대학원 치과학교실 구강악안면외과, 경상대학교 건강과학연구원) ;
  • 이종실 (경상대학교 의학전문대학원 병리학교실) ;
  • 김종렬 (부산대학교 치의학전문대학원 구강악안면외과학교실) ;
  • 박봉욱 (경상대학교 의학전문대학원 치과학교실 구강악안면외과, 경상대학교 건강과학연구원)
  • Byun, June-Ho (Department of Oral and Maxillofacial Surgery, School of Medicine and Institute of Health Science, Gyeongsang National University) ;
  • Lee, Jong-Sil (Department of Pathology, School of Medicine, Gyeongsang National University) ;
  • Kim, Jong-Ryoul (Department of Oral and Maxillofacial Surgery, School of Dentistry, Pusan National University) ;
  • Park, Bong-Wook (Department of Oral and Maxillofacial Surgery, School of Medicine and Institute of Health Science, Gyeongsang National University)
  • 발행 : 2009.01.31
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초록

Benign myoepithelioma (BME) and malignant myoepithelioma (MME) of the salivary gland are very rare and its biologic behavior has not been clarified fully. Although, cases reports for BME and MME were increased in recent, their diagnostic criteria were not completely established. We describe herein a case of BME of the parotid gland and a case of MME of the palatal minor gland, respectively. Histologically, multinodular growth pattern, infiltration to adjacent tissues, and hyalinized and myxoid matrix were observed in MME, that were different histologic features compared with BME. Strong immunoreactivities for the S-100 protein and vimentin were detected in the tumor cells of BME and MME. In specimen of MME, moderately expressed p53 and strongly expressed p63 were detected. However, in specimen of BME, p53 was negatively and p63 was weakly expressed, respectively. In conclusion, the expression patterns of p53 and p63 as well as histologic aggressiveness might be used to diagnose the MME.

키워드

참고문헌

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