References
- Blennow, K., de Leon, M.J., Zetterberg H. Alzheimer's disease. Lancet. 368(9533):387-403, 2006 https://doi.org/10.1016/S0140-6736(06)69113-7
- Selkoe, D.J., Schenk, D. Alzheimer's disease: molecular understanding predicts amyloid-based therapeutics. Annu Rev Pharmacol Toxicol. 43: 545-584, 2003 https://doi.org/10.1146/annurev.pharmtox.43.100901.140248
- Downey, D. Pharmacologic management of Alzheimer disease. J Neurosci Nurs. 40(1):55-59, 2008 https://doi.org/10.1097/01376517-200802000-00009
- 錢鏡湖, 辨證奇問全書. 台北, 甘地出版社, pp 222-225, 233-235, 1990.
- 陳士鐸. 石室秘錄. 北京, 中國中醫藥出版社, p 125, 1991
- 洪元植. 精校黃帝內經素問. 서울, 東洋醫學硏究院, pp 37, 124, 196, 229, 217-218, .229, 1985
- 朱震亨. 金櫃鉤玄. 서울, 鼎談出版社 pp 306-307, 1992
- 張介賓. 張氏景岳全書. 서울, 翰成社, pp 610-611, 1978
- 대한한방신경정신과학회편. 한방신경정신의학. 서울, 집문당, pp 311-320, 324-333, 2007
- 陳師文. 中醫學大系, 太平惠民和劑局方. 서울, 도서출판 鼎談, 9(147):537, 1990.
- 신재용 편저. 方藥合編解說. 서울, 성보사, p 37, 1988
- 김현주, 이상룡. 加味補陽還五湯과 八味合聰明湯의 microglia 보호, 항산화 및 acetylcholinesterase 억제 효과. 동의신경정신과학회지 19(2):65-75, 2008
- 유종호, 이상택, 한윤승, 김근우, 구병수, 김헌일. 황련청심음(黃連淸心飮)의 항산화 및 AChE 억제 효과에 관한 연구. 동의신경정신과학회지 17(1):1-16, 2006
-
이병훈, 박선영, 최철홍, 이은경, 정대규. 紫河車 藥鍼이
$\beta$ A로 유도된 Alzheimer's Disease 병태 모델에 미치는 영향. 동의생리병리학회지 19(2):41-64, 2008 - 최강욱, 정인철. 天王補心丹 열수추출물, 초미세분말제형이 Alzheimer's Disease 병태 모델에 미치는 영향. 동의생리병리학회지 19(2):77-93, 2008
-
서규태. 鹿茸大補湯이
$\beta$ -amyloid로 誘導된 Alzheimer's Disease 病態 모델에 미치는 影響. 대구한의대학교 대학원, 2007 - 송호철, 김성훈. 加味蔘笭白朮散 hexane세분획의 抗轉移 및 혈관형성억제작용에 대한 연구. 동의생리병리학회지. 15(6):967-974, 2001
- 김영진. 蔘笭白朮散의 Indomethacin 유도 위점막손상에 미치는 抗酸化效果, 동국대학교 대학원, 1998
- 송대섭. 蔘笭白朮散의 효능에 관한 실험적 연구, 경희대학교 대학원, 1993
- 許浚. 東醫寶鑑. 서울, 법인문화사, p 1158, 1999
- Banker G., Goslin, K. Culturing nerve cells, second edition. MIT Press, Cambridge, USA, 2002
- 대한치매학회. 치매 임상적 접근. 서울, 아카데미아, pp23-24, 30-34, 201, 233-236, 2006
- Bierer, L.M., Haroutunian, V., Gabriel, S., Knott, P.J., Carlin, L.S., Purohit, D.P., Perl, D., Dchmeridler, J., Kanof, P. and Davis, K.L. Neurochemical correlates of dementia severity in Alzheimer's disease: relative importance of the cholinergic deficits. Journal of Neurochemistry. 64: 749-760, 1995 https://doi.org/10.1046/j.1471-4159.1995.64020749.x
- 이광우. 임상신경학. 서울, 고려의학, pp 203-208, 2002
- National Institute on Aging. National Institute on Health, Progress Report on Alzheimer's Disease, 1999
- acquevel, M., Lebeurrier, N., Cheenne, S., Vivien, D. Cytokines in neuroinflammation and Alzheimer's disease, Current Drug Targets. 5(6):529-534, 2004 https://doi.org/10.2174/1389450043345308
- Kuhl, D.E., Koeppe, R.A., Minoshima, S., Snyder, S.E., Ficaro, E.P., Foster, N.L., Frey, K.A., Kilbourn, M.R. In vivo mapping of cerebral acetylcholinesterase activity in aging and Alzheimer's disease. Neurology. 52(4):691-699, 1999 https://doi.org/10.1212/WNL.52.4.691
- Mhatre, M., Floyd, R.A., Hensley, K. Oxidative stress and neuroinflammation in Alzheimer's disease and amyotrophic lateral sclerosis: common links and potential therapeutic targets, Journal of Alzheimers disease. 6(2):147-157, 2004. https://doi.org/10.3233/JAD-2004-6206
- 안준익, 이용성. Beta-amyloid의 분자생물학. 한양의대학술지, 21(1):11-16, 2001
- de Vente, J., Markerink-van Ittersum, M., van Abeelen, J., Emson, P.C., Axer, H., Steinbusch, H.W. NO-mediated cGMP synthesis in cholinergic neurons in the rat forebrain , effects of lesioning dopaminergic or serotonergic pathways on nNOS and cGMP synthesis, Eur J Neurosci. 12(2):507-519, 2000 https://doi.org/10.1046/j.1460-9568.2000.00927.x
- Trabace, L., Cassano, T., Steardo, L., Pietra, C., Villetti, G., Kendrick, K.M., Cuomo, V. Biochemical and neurobehavioral profile of CHF2819, a novel, orally active acetylcholinesterase inhibitor for Alzheimer's disease, J Pharmacol Exp Ther. 294(1):187-194, 2000
- 李尙仁 외. 방제학. 서울, 영림사, p 278, 1999.
- 徐㚆霖 외 2인. 脾胃理論與臨床, 湖南, 湖南科學技術出版社, pp 28-36, 69-85, 121, 127-147, 1990
- 北京中醫學院中藥方劑敎硏組, 湯頭歌訣白話解, 北京, 人民衛生出版社, pp 56-57, 1995
- 江克明, 包明蕙. 簡明方劑辭典. 上海, 上海科學技術出版社, p 699, 1989
- 이향중 외 4인. 중의방제적약리급임상응용, 북경, 人民衛生出版社, pp 232-235, 1992
- Selkoe, D.J. Deciphering the genesis and fate of amyloid β-protein yields novel therapies for Alzheimer disease. J Clin Invest. 110(10):1375-1381, 2002. https://doi.org/10.1172/JCI0216783
- Kobayashi, K., Hayashi, M., Nakano, H., Shimazaki, M., Sugimori, K., Koshino, Y. Correlation between astrocyte apoptosis and Alzheimer changes in gray matter lesions in Alzheimer's disease. J Alzheimers Dis. 6(6):623-632, 673-681, 2004
-
Paradis, S., Sacchetti, B., Balduzzi, M., Gaudi, S., Malchiodi-Albedi, F. Astrocyte modulation of in vitro
$\beta$ -amyloid neurotoxicity. Glia. 46(3):252-260, 2004 https://doi.org/10.1002/glia.20005 - Okada, S., Nakamura, M., Katoh, H., Miyao, T., Shimazaki, T., Ishii, K., Yamane, J., Yoshimura, A., Iwamoto, Y., Toyama, Y., Okano, H. Conditional ablation of Stat3 or Socs3 discloses a dual role for reactive astrocytes after spinal cord injury, Nat Med, 12(7):829-834, 2006 https://doi.org/10.1038/nm1425
- Rich, T., Watson, C.J., Wyllie, A. Apoptosis: the germs of death. Nat Cell Biol. 1(3):69-71, 1999 https://doi.org/10.1038/11038
- Vassar, R. Caspase-3 cleavage of GGA3 stabilizes BACE: implications for Alzheimer's disease, Neuron, 54(5):671-673, 2007 https://doi.org/10.1016/j.neuron.2007.05.018
- Leung, L.S., Shen, B., Nagalingam, N. and Ma, J. Cholinergic Activity Enhances Hippocampal Long-Term Potentiation in CA1 during Walking in Rats J. Neurosci.. 23: 9297-9304, 2003
- Weiss, C., Preston, A.R., Matthew, M. Oh, Roy D., Schwarz, Devin Welty and John F. Disterhoft. The M1 Muscarinic Agonist CI-1017 Facilitates Trace Eyeblink Conditioning in Aging Rabbits and Increases the Excitability of CA1 Pyramidal Neurons. J. Neurosci. 20: 783-790, 2000
- Oh, M.M., Power, J.M., Lucien, T., Thompson, Pamela, L., Moriearty, John F. Disterhoft. Metrifonate Increases Neuronal Excitability in CA1 Pyramidal Neurons from Both Young and Aging Rabbit Hippocampus. J. Neurosci.. 19: 1814-1823, 1999 https://doi.org/10.1523/JNEUROSCI.19-05-01814.1999
- Raschetti, R., Albanese, E., Vanacore, N., Maggini, M. Cholinesterase inhibitors in mild cognitive impairment: a systematic review of randomised trials. PLoS Med. 4(11):338, 2007 https://doi.org/10.1371/journal.pmed.0040338
-
Villarroya, M., Garc
$\'{\i}$ a, A.G., Marco-Contelles, J., L$\'{o}$ pez, M.G. An update on the pharmacology of galantamine. Expert Opin Investig Drugs. 16(12):1987-1998, 2007 https://doi.org/10.1517/13543784.16.12.1987 - During, M.J., Symes, C.W., Lawlor, P.A., Lin, J., Dunning, J., Fitzsimons, H.L., Poulsen, D., Leone, P., Xu, R., Dicker, B.L., Lipski, J., Young, D. An oral vaccine against NMDAR1 with efficacy in experimental stroke and epilepsy. Science. 287(5457):1453-1460, 2000 https://doi.org/10.1126/science.287.5457.1453
- Yee, A.S., Longacher, J.M., Staley, K.J. Convulsant and anticonvulsant effects on spontaneous CA3 population bursts. J Neurophysiol. 89(1):427-441, 2003 https://doi.org/10.1152/jn.00594.2002
- Wallenstein, G.V., Hasselmo, M.E. Functional transitions between epileptiform-like activity and associative memory in hippocampal region CA3. Brain Res Bull. 43(5):485-493, 1997 https://doi.org/10.1016/S0361-9230(97)00003-8
- Leung, L.W., Yim, C.Y. Intrinsic membrane potential oscillations in hippocampal neurons in vitro. Brain Res. 553(2):261-274, 1991 https://doi.org/10.1016/0006-8993(91)90834-I
- House,r C.R. Interneurons of the dentate gyrus: an overview of cell types, terminal fields and neurochemical identity. Prog Brain Res. 163: 217-232, 2007 https://doi.org/10.1016/S0079-6123(07)63013-1