Journal of Periodontal and Implant Science

Korean Academy of Periodontology (대한치주과학회)
권호 표지

The clinical effects of a hydroxyapatite containing toothpaste for dentine hypersensitivity

민감성 치아에 대한 수산화인회석 함유 치약의 임상적 효과

  • Kim, Su-Hwan (Department of periodontology, School of dentistry, Seoul National University) ;
  • Park, Jun-Beom (Department of periodontology, School of dentistry, Seoul National University) ;
  • Lee, Chul-Woo (Department of periodontology, School of dentistry, Seoul National University) ;
  • Koo, Ki-Tae (Department of periodontology, School of dentistry, Seoul National University) ;
  • Kim, Tae-Il (Department of periodontology, School of dentistry, Seoul National University) ;
  • Seol, Yang-Jo (Department of periodontology, School of dentistry, Seoul National University) ;
  • Lee, Yong-Moo (Department of periodontology, School of dentistry, Seoul National University) ;
  • Ku, Young (Department of periodontology, School of dentistry, Seoul National University) ;
  • Chung, Chong-Pyung (Department of periodontology, School of dentistry, Seoul National University) ;
  • Rhyu, In-Chul (Department of periodontology, School of dentistry, Seoul National University)
  • 김수환 (서울대학교 치의학대학원 치주과학교실) ;
  • 박준범 (서울대학교 치의학대학원 치주과학교실) ;
  • 이철우 (서울대학교 치의학대학원 치주과학교실) ;
  • 구기태 (서울대학교 치의학대학원 치주과학교실) ;
  • 김태일 (서울대학교 치의학대학원 치주과학교실) ;
  • 설양조 (서울대학교 치의학대학원 치주과학교실) ;
  • 이용무 (서울대학교 치의학대학원 치주과학교실) ;
  • 구영 (서울대학교 치의학대학원 치주과학교실) ;
  • 정종평 (서울대학교 치의학대학원 치주과학교실) ;
  • 류인철 (서울대학교 치의학대학원 치주과학교실)
  • Published : 2009.03.31
Download PDF
⟨ Previous Next ⟩

Abstract

Purpose: The aim of this study was to compare the effectiveness of hydroxyapatite containing toothpaste with positive control toothpastes in reducing dentine hypersensitivity. Materials and methods: This clinical trial was a double-blind, randomized, parallel group comparison of two, namely hydroxyapatite containing toothpaste and strontium chloride containing toothpaste. A total of 55 subjects were included in this study. The subjects were given randomly assigned one of the two toothpastes after received tooth brushing instruction at baseline. Some clinical indices(PI, GI, PD), verbal rating score(VRS) for sensitivity to stimulus, the effect in relieving sensitivity and visual analogue scale(VAS) for sensitivity at baseline, week 2, week 4 and week 8 were assessed. All data were evaluated by intention-to-treat analysis. Results: Overall, PI and GI scores were significantly reduced compare baseline in all groups(p<0.05). In addition, there was significant difference in PI at 4 weeks and in GI at 4, 8 weeks between groups. The proportions of subjects relieved sensitivity were 70.4% in experimental group and 57.1% in control group at 8 weeks respectively. The VRS for sensitivity to three kinds of stimuli and VAS for sensitivity decreased according to time, there was no overall difference between two groups(p>0.05). Conclusion: This study demonstrated that the new hydroxyapatite containing toothpaste was similarly effective in reducing dentine hypersensitivity with pre-existing benchmark toothpaste.

Keywords

References

  1. Dowell P, Addy M. Dentine hypersensitivity - a revIew. Aetiology, symptoms and theories of pain production. J Clin Periodontol 1983;10:341-350 https://doi.org/10.1111/j.1600-051X.1983.tb01283.x
  2. Canadian Advisory Board on Dentin Hypersensitivity. Consensus-Based Recommendations for the Diagnosis and Management of Dentin Hypersensitivity. J Can Dent Assoc 2003;69:221-228
  3. Jacobsen PL, Bruce G. Clinical Dentin Hypersensitivity: Understanding the Causes and Prescribing a Treatment. J Contemp Dent Pract 2001;2:1-12
  4. Irwin CR, McCusker P. Prevalence of dentine hypersensitivity in a general dental population. J Ir Dent Assoc 1997;43:7-9
  5. Fischer C, Fischer RG, Wennberg A. Prevalence and distribution of cervical dentine hypersensitivity in a population in Rio de Janeiro, Brazil. J Dent 1992;20:272-276 https://doi.org/10.1016/0300-5712(92)90043-C
  6. Rees JS, Addy M. A cross-sectional study of dentine hypersensitivity. J Clin Periodontol 2002;29:997-1003 https://doi.org/10.1034/j.1600-051X.2002.291104.x
  7. West NX. Dentine hypersensitivity: preventive and therapeutic approaches to treatment. Periodontol 2000 2008;48: 31-41 https://doi.org/10.1111/j.1600-0757.2008.00262.x
  8. Rosenthal MW. Historic review of the management of tooth hypersensitivity. Dent Clin North Am 1990;34:403-427
  9. M. Brannstrom. Sensitivity of dentine. Oral Surg Oral Med Oral Pathol 1966;21 :517-526 https://doi.org/10.1016/0030-4220(66)90411-7
  10. Schiff T, He T, Sagel L, Baker R. Efficacy and safety of a novel stabilized stannous fluoride and sodium hexametaphosphate dentifrice for dentinal hypersensitivity. J Contemp Dent Pract 2006;7: 1-8
  11. Orchardson R, Gillam DG. Managing dentin hypersensitivity. J Am Dent Assoc 2006; 137 :990-998 https://doi.org/10.14219/jada.archive.2006.0321
  12. Walters PA. Dentinal hypersensitivity: a review. J Contemp Dent Pract 2005;6:107-117
  13. Niwa M, Sato T, Li W, Aoki H, Aoki H, Daisaku T. Polishing and whitening properties of toothpaste containing hydroxyapatite. J Mater Sci Mater Med 2001;12:277-281 https://doi.org/10.1023/A:1008927502523
  14. Park JJ, Park 18, Kwon YH, Herr Y, Chung JH. The effects of microcrystalline hydroxyapatitie containing toothpaste in the control of tooth hypersensitivity. J Korean Acad Periodontol 2005;35:577-590 https://doi.org/10.5051/jkape.2005.35.3.577
  15. Silness J, Loe H. Periodontal disease 10 pregnancy, II. Correlation between oral hygiene and periodontal condition. Acta Odontol Scand 1964;22:121-135 https://doi.org/10.3109/00016356408993968
  16. Loe H, Silness J. Periodontal disease in pregnancy, I. Prevalenca and severity. Acta Odontol Scand 1963;21:533-551 https://doi.org/10.3109/00016356309011240
  17. Clark DC, AI-Joburi W, Chan EC. The efficacy of a newdentifrice in treating dentin sensitivity: effects of sodium citrate and sodium fluoride as active ingredients. J Periodontal Res 1987;22:89-93 https://doi.org/10.1111/j.1600-0765.1987.tb01545.x
  18. Kanapka JA. Over-the-counter dentifrices in the treatment of tooth hypersensitivity. Review of clinical studies. Dent Clin North Am 1990;34:545-560
  19. Minkoff S, Axelrod S. Efficacy of strontium chloride in dental hypersensitivity. J Periodontol 1987;58:470-474 https://doi.org/10.1902/jop.1987.58.7.470
  20. Kim JH, Kim SU, Kwon YH, Lee MS. Clinical evaluation of microcrystalline hydroxyapatite toothpaste in the control of dentin hypersensitivity. J Korean Acad Periodontol 1984; 14:229-240
  21. Lim SC, Choi JC, Herr Y, Lee MS. Clinical evaluation of microcrystalline hydroxyapatite containing toothpaste in the contol of dentin hypersensitivity after periodontal treatment. J Korean Acad Periodontol 1993;23:127-134
  22. Kim MS, Chae GJ, Choi SH et al. Effect of hydroxyapatite containing dentifrice on teeth hypersensitivity after periodontal therapy. J Korean Acad Periodontol 2008;38:1-6 https://doi.org/10.5051/jkape.2008.38.1.1
  23. Green BL, Green ML, McFall WT Jr. Calcium hydroxide and potassium nitrate as desensitizing agents for hypersensitive root surfaces. J Periodontol 1977;48:667-672 https://doi.org/10.1902/jop.1977.48.10.667
  24. Owens J, Addy M, Faulkner J. An 18-week home-use study comparing the oral hygiene and gingival health benefits of triclosan and fluoride toothpastes. J Clin Periodontol 1997;24:626-631 https://doi.org/10.1111/j.1600-051X.1997.tb00239.x
  25. Poulsen S, Errboe M, Lescay Mevil Y, Glenny AM. Potassium containing toothpastes for dentine hypersensitivity. Cochrane Database Syst Rev 2006;19:CD001476