The Clinical Results of Surgical Treatment for Sternoclavicualr Septic Arthritis

흉늑쇄 패혈성 관절염의 수술적 치료의 임상결과

  • Kim, Shin (Department of Thoracic and Cardiovascular Surgery, Hallym University Sacred Heart Hospital, Hallym University College of Medicine) ;
  • Lee, Hee-Sung (Department of Thoracic and Cardiovascular Surgery, Kangnam Sacred Heart Hospital, Hallym University College of Medicine) ;
  • Kim, Kun-Il (Department of Thoracic and Cardiovascular Surgery, Hallym University Sacred Heart Hospital, Hallym University College of Medicine) ;
  • Cho, Sung-Woo (Department of Thoracic and Cardiovascular Surgery, Kangdong Sacred Heart Hospital, Hallym University College of Medicine) ;
  • Kim, Hyoung-Soo (Department of Thoracic and Cardiovascular Surgery, Chuncheon Sacred Heart Hospital, Hallym University College of Medicine) ;
  • Shin, Ho-Seung (Department of Thoracic and Cardiovascular Surgery, Hangang Sacred Heart Hospital, Hallym University College of Medicine) ;
  • Lee, Jae-Woong (Department of Thoracic and Cardiovascular Surgery, Hallym University College of Medicine) ;
  • Hong, Ki-Woo (Department of Thoracic and Cardiovascular Surgery, Hallym University College of Medicine)
  • 김신 (한림대학교 의과대학 성심병원 흉부외과학교실) ;
  • 이희성 (한림대학교 의과대학 강남성심병원 흉부외과학교실) ;
  • 김건일 (한림대학교 의과대학 성심병원 흉부외과학교실) ;
  • 조성우 (한림대학교 의과대학 강동성심병원 흉부외과학교실) ;
  • 김형수 (한림대학교 의과대학 춘천성심병원 흉부외과학교실) ;
  • 신호승 (한림대학교 의과대학 한강성심병원 흉부외고학교실) ;
  • 이재웅 (한림대학교 의과대학 흉부외과학교실) ;
  • 홍기우 (한림대학교 의과대학 흉부외과학교실)
  • Published : 2009.04.05

Abstract

Background: Sternoclavicular septic arthritis manifests serious complications such as abscess, osteomyelitis, mediastinitis and empyema; therefore, a prompt diagnosis and appropriate treatment are necessary. Material and Method: The treatment results of eight patients with sternoclavicular septic arthritis and who had been surgically treated at our institutions between September 2005 and July 2008 were retrospectively reviewed. The surgical treatment they underwent was en bloc resection, including partial resection of the sternum, the clavicular head and the 1st rib. Result: The patients ranged in age from 40 to 74 years with an average of $55.1{\pm}10.3$ years. Five were men and three were women. There were 6 patients with spontaneous sternoclavicular septic arthritis and 2 patients had their condition induced by central venous catheters. The pathogens isolated from the patients’ blood and wounds were MRSA (3), Streptococcus intermedius (1), Streptococcus agalactiae (1) and Pseudomonas luteola (1). One patient expired from aggravation of preoperative sepsis on POD 31. Conclusion: The life-threatening complications from sternoclavicular septic arthritis can progress and lead to death unless appropriate treatment is administered. A prompt diagnosis, appropriate antibiotics therapy and effective surgical treatment such as radical en bloc resection can reduce the morbidity and mortality of this malady.

배경: 흉늑쇄 패혈성 관절염은 농양, 골수염, 종격동염, 농흉 등의 심각한 합병증이 동반되는 흉늑쇄관절부 감염으로 신속한 진단 및 적절한 치료가 이루어져야 한다. 대상 및 방법: 2005년 9월부터 2008년 7월까지 본 의료원에서 흉늑쇄 패혈성 관절염으로 수술적 치료를 받은 8명의 환자를 대상으로 수술적 치료결과를 후향적으로 조사하였다. 흉늑쇄 패혈성 관절염의 수술적 치료로는 광범위 흉골, 쇄골두 및 첫번째 늑골의 부분 절제를 포함하는 근치절제술을 시행하였다. 결과: 환자의 연령 분포는 40세에서 74세까지였고 평균 연령은 $55.1{\pm}10.3$세였다. 남자가 5명, 여자가 3명이었다. 자연성 흉늑쇄 패혈성 관절염이 6예이었고, 중심정맥관 거치 후에 발생한 흉늑쇄 관절염이 2예였다. 흉늑쇄패혈성 관절염의 위치는 모두 우측이었다. 환자의 혈액 및 염증부위, 객담배양에서 동정된 균종은 MRSA 3예, Streptococcus intermedius 1예, Streptococcus agalactiae 1예, Pseudomonas luteola 1예였다. 근치절제술 환자 중 1명의 환자가 수술 전 패혈증이 진행하여 수술 후 31일째 사망하였다. 결론: 흉늑쇄 패혈성 관절염은 적절한 치료가 이루어지지 않으면 합병증으로 사망까지 이를 수 있는 질환으로 신속한 진단과 적절한 항생제의 사용 및 광범위 근치 절제술 등의 효과적인 치료를 통하여 이환율과 사망률을 낮출 수 있을 것이다.

Keywords

References

  1. Yood YA, Goldenberg DL. Sternoclavicular joint arthritis. Arthritis Rheum 1980;23:232-9 https://doi.org/10.1002/art.1780230215
  2. Western VC, Jones AC, Bradbury N, Fawthrop F, Doherty M. Clinical features and outcomes of septic arthritis in a single UK health district 1982-1991. Ann Rheum Dis 1999;58:214-9 https://doi.org/10.1136/ard.58.4.214
  3. Linthoudt DV, Velan F, Ott H. Abscess formation in sternoclavicular joint septic arthritis. J Rheumatol 1989;16:413-4
  4. Wohlgethan JR, Newberg AH, Reed JI. The risk of abscess from sternoclavicular arthritis. J Rheumatol 1988;15:1302-6
  5. Tecce PM, Fishman EK. Spiral CT with multiplanar reconstruction in the diagnosis of sternoclavicular osteomyelitis. Skeletal Radiol 1995;24:275-81
  6. Pollack MS. Staphylococcal mediastinitis due to sternoclavicular pyarthrosis: CT appearance. J Comput Assist Tomogr 1990;14:924-7 https://doi.org/10.1097/00004728-199011000-00011
  7. Chen WS, Wan YL, Lui CC, Lee TU, Wang KC. Extrapleural abscess secondary to infection of the sternoclavicular joint. J Bone Joint Surg 1993;75:1835-9
  8. Ross JJ, Shamsuddin H. Sternoclavicular septic arthritis: review of 180 cases. Medicine 2004;83:139-48 https://doi.org/10.1097/01.md.0000126761.83417.29
  9. Muir SK, Kinsella PL, Trebilcock RG, Blackstone IW. Infectious arthritis of the sternoclavicular joint. Can Med Assoc J 1985;132:1289-90
  10. Lindsey RW, Leach JA. Sternoclavicular osteomyelitis and pyarthrosis as a complication of subclavian vein catheterization: a case report and review of the literature. Orthopedics 1984;7:1017-21
  11. Hunter D, Moran JF, Venezio FR. Osteomyelitis of the clavicle after Swan-Ganz catheterization. Arch Intern Med 1983;143:153-4 https://doi.org/10.1001/archinte.143.1.153
  12. Sonobe M, Miyazaki M, Nakagawa M, et al. Descending necrotizing mediastinitis with sternocostoclavicular osteomyelitis and partial thoracic empyema: report of a case. Surg Today 1999;29:1287-9 https://doi.org/10.1007/BF02482226
  13. Linscheid RL, Kelly PJ, Martin WJ, Rontana RS. Monarticular bacterial arthritis of the sternoclavicular joint. JAMA 1961;178:421-2 https://doi.org/10.1001/jama.1961.73040430016018a
  14. Gerscovich EO, Greenspan A. Osteomyelitis of the clavicle: clinical, radiologic, and bacteriologic findings in ten patients. Skeletal Radiol 1974;23:205-10
  15. Alexander PW, Shin MS. CT manifestation of sternoclavicular pyarthrosis in patients with intravenous drug abuse. J Comput Assist Tomogr 1990;14:104-6 https://doi.org/10.1097/00004728-199001000-00019
  16. Gerscovich EO, Greenspan A. Osteomyelitis of the clavicle: clinical, radiologic, and bacteriologic findings in ten patients. Skeletal Radiol 1974;23:205-10
  17. Song HK, Guy TS, Kaiser LR, Shrager JB. Current presentation and optimal surgical management of sternoclavicular joint infections. Ann Thorac Surg 2002;73:427-31 https://doi.org/10.1016/S0003-4975(01)03390-2