Archives of Plastic Surgery

Korean Society of Plastic and Reconstructive Surgeons (대한성형외과학회)
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A Case Report of Palatoplasty in a Patient with Clotting Factor Ⅹ Deficiency

선천성 혈액 응고 인자 Ⅹ(10번) 결핍증 환아에서 구개성형술의 증례보고

  • Kim, Suk Wha (Department of Plastic and Reconstructive Surgery, Seoul National University College of Medicine) ;
  • Jeong, Eui Cheol (Department of Plastic and Reconstructive Surgery, Seoul National University College of Medicine) ;
  • Yun, Byung Min (Department of Plastic and Reconstructive Surgery, Korea University College of Medicine) ;
  • Choi, Tae Hyun (Department of Plastic and Reconstructive Surgery, Seoul National University College of Medicine) ;
  • Kang, Hyoung Jin (Department of Pediatrics, Seoul National University College of Medicine)
  • 김석화 (서울대학교 의과대학 성형외과학 교실) ;
  • 정의철 (서울대학교 의과대학 성형외과학 교실) ;
  • 윤병민 (고려대학교 의과대학 성형외과학 교실) ;
  • 최태현 (서울대학교 의과대학 성형외과학 교실) ;
  • 강형진 (서울대학교 의과대학 소아과학 교실)
  • Published : 2009.11.15
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Abstract

Purpose: Clotting factor X deficiency is one of the most uncommon coagulation disorders. The authors describe a case of cleft palate in a patient with a congenital clotting factor X deficiency. Methods: In pediatric patients with a cleft palate, the coagulation problem is more worrisome, because they are more sensitive to blood than adults, and because postoperative bleeding can cause blood ingestion with subsequent vomiting, aspiration, and airway obstruction. To prevent hemorrhagic complications in the described case, fresh frozen plasma (FFP) was administered every 24 hrs from the day before surgery to the second postoperative day. Results: Good hemostasis, normal healing, and no complications was shown postoperatively. Conclusion: The replacement of fresh frozen plasma was useful in the case of congenital clotting factor deficiency for bleeding prophylaxis in cleft palate operation.

Keywords

References

  1. Uprichard J, Perry DJ: Factor X deficiency. Blood Rev 16: 97, 2002 https://doi.org/10.1054/blre.2002.0191
  2. Kim SW, Lee HK, Lee JK: Palatoplasty with modified furlow's operation. J Korean Soc Plast Reconstr Surg 23: 1367, 1996
  3. Rintala A: Blood loss in cleft palate surgery. Acta Chir Scand. 129: 288, 1965
  4. Dendy RA, Davies JR, Gorst DW: A tongue resection in macroglossia due to primary amyloidosis. Br J Oral Maxillofac Surg 27: 329, 1989 https://doi.org/10.1016/0266-4356(89)90047-8
  5. Ott R, Pfeiffer RA: Evidence that activities of coagulation factors VII and X are linked to chromosome 13 Hum Hered 34: 123, 1984 https://doi.org/10.1159/000153447
  6. Pirrello R, Siragusa S, Giambona C, D'Arpa S, Cordova A, Moschella F: Bleeding prophylaxis in a child with cleft palate and factor VII deficiency: A case report. Cleft Palate Craniofac J 43: 108, 2006 https://doi.org/10.1597/04-165.1
  7. Park CG, Kum IS: Surgery in cleft lip and palate with hemophilia A. J Korean Soc Plast Reconstr Surg 18: 907, 1991