Food Science and Biotechnology

Korean Society of Food Science and Technology (한국식품과학회)
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Less Weight Gain in Obese Rats by Feeding Biocellulose

  • Published : 2009.02.28
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Abstract

This study evaluated the effect of biocellulose and the diet formulation on reducing body weight gain of obese rats induced by high-fat diet for 10 weeks. Thirty male Sprague-Dawley rats were randomly assigned to high-fat diet group (OB-CON), high-fat diet group containing 5% biocellulose (OB-BIO), and high-fat diet group containing 5% dietary formulation (OB-DF). After feeding each diet for additional 10 weeks, body weight gains of OB-BIO and OB-DF groups were lower by 3.3 and 4.8%, respectively as compared with that of OB-CON group. Although not significant, measured values of the perirenal and visceral fat pads of OB-BIO and OB-DF groups were lower than those of the OB-CON group. The weight of interscapular brown adipose tissue did not show significant difference in all groups. The size of adipocyte in rats was lower in both OB-BIO and OB-DF groups. Thus, biocelluose and the diet formulation showed the anti-obesity effect.

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References

  1. Blundell JE, Stubbs RJ, Golding C, Croden F, Alam R, Whybrow S, Le Noury J, Lawton CL. Resistance and susceptibility to weight gain: Individual variability in response to a high-fat diet. Physiol. Behav. 86: 614-622 (2005) https://doi.org/10.1016/j.physbeh.2005.08.052
  2. Gortmaker SL. Social and economic consequences of obesity. New Engl. J. Med. 348: 2082-2090 (1993) https://doi.org/10.1056/NEJMoa022207
  3. Kang KJ, Lim SJ, Jeong JH, Han HK, Choi SS, Kim MH, Kwon SY. Effects of wax guard on weight, triglyceride, leptin, and fat cell size in rats fed on a high fat diet. Korean J. Nutr. 36: 446-451 (2003)
  4. Lee SH, Park HJ, Cho SY, Jung IK, Cho YS. Kim TY, Hwang HG, Lee YS. Supplementary effect of the high dietary fiber rice on blood glucose in diabetic mice. Korean J. Nutr. 37: 75-80 (2004)
  5. Slavin JL. Dietary fiber and body weight. Nutrition 21: 411-418 (2005) https://doi.org/10.1016/j.nut.2004.08.018
  6. Han DS, Kwon EK, Kim DW, Kim YE, Lee CH. Kim IH. Biocellulose reduces body weight gain of rats fed high-fat diet. Food Sci. Biotechnol. 15: 70-76 (2006)
  7. Raghavendra SN, Rastogi NK, Raghavarao KSMS, Tharanathan RN. Dietary fiber from coconut residue: Effects of different treatments and particle size on the hydration properties. Eur. Food Res. Technol. 218: 563-567 (2004) https://doi.org/10.1007/s00217-004-0889-2
  8. Heaton KW. Food fiber as an obstacle to energy intake. Lancet 22: 1418-1421 (1973)
  9. Jenkins D, Wolever T, Ran AV, HegeIe RA, Mitchell SJ, Ranson T, Boctor DL, Spadafora PJ, Jenkins AL, Mehling C, Relle LK, Connelly PW, Story JA, Furumoto EJ, Corey P, Wursch P. Effect of blood lipids of very high intakes of fiber in diets low in saturated fat and cholesterol. New Engl. J. Med. 329: 21-26 (1993) https://doi.org/10.1056/NEJM199307013290104
  10. Saris WH. Glycemic carbohydrate and body weight regulation. Nutr. Rev. 61: S10-S16 (2003) https://doi.org/10.1301/nr.2003.may.S10-S16
  11. Kelsay JL, Behall KM, Prather ES. Effect of fiber from fruits and vegetables on metabolic responses of human subjects. Am. J. Clin. Nutr. 31: 1149-1156 (1978) https://doi.org/10.1093/ajcn/31.7.1149
  12. Cho SH, Lee JY, Choi YS, Choi KH. Dietary effects of fiber produced from gluconoacetobacter hansenii on digestive tract and lipid metabolism in rats. J. Korean Soc. Food Sci. Nutr. 31: 802-807 (1997) https://doi.org/10.3746/jkfn.2002.31.5.802
  13. SLC. Experimental Animals. Japan SLC, Inc., Shizuoka Prefecture, Japan. pp. 1-2 (2005)
  14. Lee BH, Cho KD. Effects of herb and fiber-rich dictary supplement on body weight, body fat, blood lipid fractions, and bowel habits in collegians. J. Korean Soc. Food Sci. Nutr. 34: 644-651 (2005) https://doi.org/10.3746/jkfn.2005.34.5.644
  15. Yook HS, Kim JO, Choi JM, Kim DH, Cho SK, Byun MW. Changes of nutritional characteristics and serum cholesterol in rats by the intake of dietary fiber isolated from ascidian (Halocynthia roretzi) tunic. J. Korean Soc. Food Sci. Nutr. 32: 474-478 (2003) https://doi.org/10.3746/jkfn.2003.32.3.474
  16. Jensen MD, Research techniques for body composition assessment. J. Am. Diet. Assoc. 92: 454-460 (1992)
  17. Mermel VL. Old paths new directions: The use of functional foods in the treatment of obesity. Trends Food Sci. Technol. 15: 532-540 (2004) https://doi.org/10.1016/j.tifs.2004.03.0054
  18. Klaus S. Adipose tissue as a regulator of energy balance. Curr. Drug Targets 5: 241-250 (2004) https://doi.org/10.2174/1389450043490523
  19. Kathleen ML, Sylvia Escott-Stump MA. Kreause's Food, Nutrition & Diet Therapy. 11th ed. Saunders Press, St. Louis, MO, USA. p. 560 (2000)
  20. Cornelius P, MacDougald OA, Lane MD. Regulation of adipocyte development. Aunu. Rev. Nutr. 14: 99-129 (1994) https://doi.org/10.1146/annurev.nu.14.070194.000531
  21. Gregoire FM, Smas CM, Sul HS. Understanding adipocyte differentiation. Physiol. Rev. 78: 783-809 (1998) https://doi.org/10.1152/physrev.1998.78.3.783
  22. Lee GE, Lyu JS, Kim YT, Song YK, Kim KS, Lee MH. Clinical characteristics of Korean diabetic patients classified by fasting plasma C-peptide level and degree of obesity. Korean J. Intern. Med. 42: 315-321 (1992)
  23. Elam MH, Wilcox HG, Cagen LM, Deng X, Raghow R, Kumar P, Heimberg M, Russell JC. Increased hepatic VLDL secretion, lipogenesis, and SREBP-1 expression in the corpulent JCRLA-cp rat. J. Lipid Res. 42: 2039-2048 (2001)