Korean Journal of Pharmacognosy (생약학회지)

The Korean Society of Pharmacognosy (한국생약학회)
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Phenolic Compounds Isolated from the Leaves of Angelica keiskei Showing DPPH Radical Scavenging Effect

신선초에서 페놀성 화합물의 분리 및 이들의 DPPH 라디칼 소거활성

  • Jo, Hyun-Woo (Department of Oriental Medicine Resources and Research Institute of Korean Oriental Medicine, Sunchon National University) ;
  • Park, Jong-Cheol (Department of Oriental Medicine Resources and Research Institute of Korean Oriental Medicine, Sunchon National University)
  • 조현우 (국립순천대학교 한약자원학과 및 한의약연구소) ;
  • 박종철 (국립순천대학교 한약자원학과 및 한의약연구소)
  • Published : 2008.06.30
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Abstract

From the leaves of Angelica keiskei (Umbelliferae), luteolin, protocatechuic acid, guaijaverin, hyperoside and cynaroside were isolated and characterized by spectral data. Luteolin and protocatechuic acid showed potent DPPH radical scavenging activity.

Keywords

References

  1. Enoki, T., Ohnogi, H., Nagamine, K., Kudo, Y., Sugiyama, K., Tanabe, M., Kobayashi, E., Sagawa, H. and Kato, I. (2007) Antidiabetic activities of chalcones isolated from a japanese herb, Angelica keiskei, J. Agri. Food Chem. 55(15): 6013-6017 https://doi.org/10.1021/jf070720q
  2. 송주택 (1994) 한국자원식물, 220, 미도문화사, 서울
  3. 박은령, 이해정, 이명렬, 김경수 (1997) 신선초의 식용부위별 향기성분, 한국식품과학회지 29(4): 641-647
  4. 김소중, 조정용, 위지향, 장미영, 임요섭, 김철, 신수철, 문제학, 박근형 (2005) 신선초에 함유된 항상화물질 Psoralen 유도체들의 단리 및 동정, 한국식품과학회지 37(4): 656-6
  5. Park, J. C., Park, J. R., Chung, S. K., Yu, Y. B., Ha, J. O. and Park, K. Y. (1997) Antimutagenic activity of the methanol extract and compounds of Angelica keiskei in the Salmonella assay system, Kor. J. Pharmacogn. 28(2): 80-83
  6. 박정로, 박석규, 조영숙, 전순실, 최성희, 박종철 (1997) Angelica keiskei 가 흰쥐의 지질대사에 미치는 영향, 한국식품영양과학회지 26(2): 308-313
  7. Loizzo, M. R., Said, A., Tundis, R., Rashed, K., Statti, G. A., Hufner, A. and Menichini, F. (2007) Inhibition of angiotensin converting enzyme (ACE) by flavonoids isolated from Ailanthus excelsa (Roxb) (Simaroubaceae), Phytother. Res., 21(1):32-36 https://doi.org/10.1002/ptr.2008
  8. 문성필, 구창섭 (2006) Characterization of low molecular weight polyphenols from Pinus radiata Bark, Food Sci. Biotechnol. 15(3): 424-430
  9. 권용수, 인고길, 김창민 (2000) 강활의 활성성분, 생약학회지 31(3): 284-287
  10. Fraisse, D., Heitz, A., Carnat, A. and Lamaison, J. L. (2000) Quercetin 3-arabinopyranoside, a major flavonoid compound from Alchemilla xanthochlora, Fitoterapia 71(4): 463-464 https://doi.org/10.1016/S0367-326X(00)00145-3
  11. 박종철, 유영법, 이종호, 최명락, 옥광대 (1996) Angelica keiskei 지상부의 화학성분, 생약학회지 27(1): 80-82
  12. Blois, M. S. (1958) Antioxidant determination by the use of a stable free radical, Nature, 181: 1199-1200 https://doi.org/10.1038/1811199a0
  13. Bravo, L. (1998) Polyphenols: Chemistry, dietary sources, metabolism and nutritional significance. Nutr. Rev. 56(11): 317 https://doi.org/10.1111/j.1753-4887.1998.tb01670.x
  14. Choi, J. S., Han, S. Y., Park, J. C., Choi, J. H and Woo, W. S. (1986) Flavonoids from the leaves of Rhododendron brachycarpum, Arch. Pharm. Res. 9(4): 233-236 https://doi.org/10.1007/BF02856638
  15. 임현우, 강성진, 박민, 윤정혜, 한병훈, 최선은, 이민우 (2006) Antioxidative and nitiric oxide production inhibitory activities of phenolic compounds from the fruits of Actinidia arguta, Nat. Prod. Sci. 12(4): 221-225
  16. 정창호, 배영일, 심기환, 최진상 (2004) 질경이 추출물의 DPPH 라디칼 소거효과 및 항균활성, 한국식품영양과학회지 33(10): 1601-1605
  17. Hatano, T. (1995) Constituents of natural medicines with scavenging effects on active oxygen species tannins and related polyphenols. Natural Medicines. 49(14): 357-363
  18. Hirano, T., Higa, S., Arimitsu, J., Naka, T., Ogata, A., Shima, Y., Fujimoto, M., Yamadori, T., Ohkawara, T., Kuwabara, Y., Kawai, M., Matsuda, H., Yoshikawa, M., Maezaki, N., Tanaka, T., Kawase, I. and Tanaka, T. (2006) Luteolin, a flavonoid, inhibits AP-1 activation by basophils, Biochem. Biophys. Res. Commun., 340(1): 1-7 https://doi.org/10.1016/j.bbrc.2005.11.157
  19. Kim, H. J., Kim, E. J., Seo, S. H., Shin, C. C., Jin, C. B., Lee, Y. S. (2006) Vanillic acid glycoside and quinic acid derivatives from gardeniae fructus, J. Nat. Prod. 69(4): 600-603 https://doi.org/10.1021/np050447r