Reproductive and Developmental Biology

  • 제32권1호
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  • Pages.51-58
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  • 2008
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  • 1738-2432(pISSN)
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  • 2288-0151(eISSN)
한국동물번식학회 (The Korean Society of Animal Reproduction)
권호 표지

복제 송아지의 임신 기간과 생시체중이 출생 후 생존율에 미치는 영향

Effects of Gestation Length and Birth Weight on Survival Rate in Cloned Korean Native Calves

  • 양병철 (농촌진흥청 축산과학원 응용생명공학과) ;
  • 임기순 (농촌진흥청 축산과학원 응용생명공학과) ;
  • 김동훈 (농촌진흥청 축산과학원 응용생명공학과) ;
  • 고응규 (농촌진흥청 축산과학원 응용생명공학과) ;
  • 황성수 (농촌진흥청 축산과학원 응용생명공학과) ;
  • 노환국 (한국농업대학 중소가축학과) ;
  • 김명직 (농촌진흥청 축산과학원 응용생명공학과) ;
  • 양보석 (농촌진흥청 축산과학원 응용생명공학과) ;
  • 이상진 (농촌진흥청 축산과학원 응용생명공학과) ;
  • 성환후 (농촌진흥청 축산과학원 응용생명공학과)
  • Yang, Byoung-Chul (Division of Animal Biotechnology, National Institute of Animal Science, RDA) ;
  • Im, Gi-Sun (Division of Animal Biotechnology, National Institute of Animal Science, RDA) ;
  • Kim, Dong-Hoon (Division of Animal Biotechnology, National Institute of Animal Science, RDA) ;
  • Ko, Yeoung-Gyu (Division of Animal Biotechnology, National Institute of Animal Science, RDA) ;
  • Hwang, Seong-Soo (Division of Animal Biotechnology, National Institute of Animal Science, RDA) ;
  • Nho, Whan-Gook (Department of Livestock, Korea National Agricultural College) ;
  • Kim, Myung-Jick (Division of Animal Biotechnology, National Institute of Animal Science, RDA) ;
  • Yang, Boh-Suck (Division of Animal Biotechnology, National Institute of Animal Science, RDA) ;
  • Lee, Sang-Jin (Division of Animal Biotechnology, National Institute of Animal Science, RDA) ;
  • Seong, Hwan-Hoo (Division of Animal Biotechnology, National Institute of Animal Science, RDA)
  • 발행 : 2008.03.31
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초록

본 연구는 체세포 복제 한우 송아지의 생산에서 생시체중과 생존성과의 관계에 대하여 살펴보고자 실시하였다. 293두의 한우 대리모에 580개의 복제란을 이식하였다. 복제란의 임신율은 이식 후 50일까지 72.3%로 높았으나, 이후 급격하게 감소하였다. 평균 임신 기간은 복제 송아지에서 287일($279{\sim}295$일)이었으며, 인공수정 송아지도 287일($255{\sim}293$일)로 각각 나타났다. 복제 송아지의 생시체중(30.3kg)은 인공수정 송아지(23.7kg)에 비하여 유의하게 높은 것으로 나타났다(p<0.05). 자연분만(n=17, 29.9kg)과 제왕절개(n=14, 32.3kg)로 태어난 복제 송아지의 생시체중은 차이가 없었다. 하지만, 생후 175일 이전에 사망한 복제 송아지(n=18, 32.8kg)의 생시체중이 175일 이상 생존한 복제 송아지(n=11, 28.3kg)보다 유의적으로 높게 나타났다(p<0.05). 흥미로운 점은 생시체중이 15kg 이하(n=5) 또는 35kg 이상(n=9)인 복제 송아지들은 모두 생후 175일 이전에 폐사하였다. 생후 175일 이전에 폐사한 복제 송아지들(n=20)의 사망 원인은 미성숙 개체 2두(10.0%), 폐와 간 이상 2두(10.0%), 폐의 원인 4두(20.0%), 기형 4두(20.0%), 출생 후 급사(sudden death syndrome) 4두(20.0%) 및 기타 원인불명이 4두(20.0%) 등으로 분류되었다. 이상의 결과를 종합하여보면, 복제 송아지의 정상 생시체중이 6개월 이상을 생존하는데 가장 중요한 요소들 중의 한 가지임을 확인하였다.

This study was performed to investigate the relation between birth weight and survivability on the production of cloned Hanwoo calves. The 580 cloned embryos were transferred into the 293 recipients. The pregnancy rate of the cloned embryos was 72.3% at 50 days after embryo transfer, and then the rate was dramatically decreased. The mean gestation lengths were 287 days in both clone (range of$279{\sim}295$ days) and artificial insemination (AI, range of $255{\sim}293$ days) calves, respectively. The mean birth weight of cloned calves (30.3kg) was significantly higher compared to that of AI calves (23.7kg) (p<0.05). Among the cloned calves, the birth weight was not different in both normal delivery (n=17, 29.9kg) and caesarean section (n=14, 32.3kg). The weight, however, was significantly higher in the clones (n=18, 32.8kg) dead within 175 days than that of the clones (n=11, 28.3kg) alive more than 175 days after birth (p<0.05). Interestingly, all cloned calves weighed <15kg (n=5) or >35kg (n=9) at birth have been dead within 175 days from the date of birth. The causes of death in the cloned calves were premature birth (n=2, 10.0%), abnormal function of lung and liver (n=2, 10.0%), abnormal function of lung (n=4, 20.0%), malformation (n=4, 20.0%), unknown (n=4, 20.0%), and sudden death syndrome (n=4, 20.0%), respectively. Our findings suggest that normal birth weight is one of the most important factors to survive more than 6 months in cloned calves.

키워드

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