Advances in pediatric surgery
- 제14권2호
- /
- Pages.153-163
- /
- 2008
- /
- 2635-8778(pISSN)
- /
- 2635-8786(eISSN)
소아에서 발생한 복강내 염증성 근섬유모세포종의 임상적 고찰
Abdominal Inflammatory Myofibroblastic Tumor in Children
- 김현영 (가천의과대학 길병원 외과) ;
- 문석배 (서울대학교 어린이병원 소아외과) ;
-
정성은
(서울대학교 어린이병원 소아외과) ;
- 이성철 (서울대학교 어린이병원 소아외과) ;
- 박귀원 (서울대학교 어린이병원 소아외과) ;
- 김우기 (서울대학교 어린이병원 소아외과)
- Kim, Hyun-Young (Department of Surgery, Gacheon Medical School Gil Hospital) ;
- Moon, Suk-Bae (Department of Pediatric Surgery, Seoul National University children's Hospital) ;
-
Jung, Sung-Eun
(Department of Pediatric Surgery, Seoul National University children's Hospital) ;
- Lee, Seong-Cheol (Department of Pediatric Surgery, Seoul National University children's Hospital) ;
- Park, Kwi-Won (Department of Pediatric Surgery, Seoul National University children's Hospital) ;
- Kim, Woo-Ki (Department of Pediatric Surgery, Seoul National University children's Hospital)
- 투고 : 2008.10.09
- 심사 : 2008.12.24
- 발행 : 2008.12.31
초록
Inflammatory myofibroblastic tumor (IMT) is a rare reactive lesion characterized by the feature of myofibroblasts and a mixed inflammatory infiltrate that rarely undergoes malignant transformation. Extrapulmonary IMTs in children have been described involving the mesentery, omentum, retroperitoneum, abdominal soft tissues, liver, bladder, mediastinum, head and neck, extremity, appendix, and kidney. Medical records of children treated with abdominal IMT between 1985 and 2005 were reviewed retrospectively. Seven children were treated for IMT with the mean age of 3 y 2 m (range, 1 y 1 m to 14 y). Tumors were located in transverse mesocolon (n=2), omentum (n=1), porta hepatis (n=2), complex site (antrum, duodenum, common bile duct, porta hepatis) (n=2). The symptoms included abdominal mass, fever, jaundice, abdominal pain and anemia. The masses were excised totally in transverse mesocolon, omentum IMT and there is no evidence of recurrence (follow-up periods: 6 y 8 m, 8 y 9 m, 4 y 10 m). In porta hepatis IMT, liver transplantations were performed and there is no evidence of recurrence (follow period: 6 y 8 m, 8 y 7 m). In one case of complex site IMT, partial excision of mass was performed and he still survived with no change of the residual tumor during follow-up period. The other one of complex site IMT denied further treatment after the biopsy. In conclusion, complete surgical excision including liver transplantation and close follow-up are mandatory for the abdominal IMT in child.