Depression in Patients with End-Stage Renal Disease

말기 신장질환자의 우울증

  • Kim, Seon-Young (Department of Psychiatry, Chonnam National University Medical School and Depression Clinical Research Center, Chonnam National University Hospital) ;
  • Kim, Jae-Min (Department of Psychiatry, Chonnam National University Medical School and Depression Clinical Research Center, Chonnam National University Hospital) ;
  • Yoon, Jin-Sang (Clinical Trial Center, Chonnam National University Hospital)
  • 김선영 (전남대학교 의과대학 정신과학교실 및 전남대학교병원 우울증 임상연구센터) ;
  • 김재민 (전남대학교 의과대학 정신과학교실 및 전남대학교병원 우울증 임상연구센터) ;
  • 윤진상 (전남대학교병원 임상시험센터)
  • Published : 2008.11.30

Abstract

Depression is common in patients with end-stage renal disease(ESRD) and has a negative effect on the quality of life, functional ability, and mortality of the patients, with a prevalence rate as high as 20-25%. Especially, the increasing tendency of mortality in ESRD patients is associated with recent or current depression, and the suicide rate is also increased by depression in patients with ESRD. Therefore, accurate detection and appropriate treatment of depression is very important in ESRD patients. Also, a deferential diagnosis is needed concerning uremic symptoms and depression in ESRD patients. However, there has been little data so far particularly in terms of randomized clinical trials. This review focused on the recent knowledge of depression in ESRD, and could encourage clinical study and trials in this field.

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