Journal of the Korean Applied Science and Technology (한국응용과학기술학회지)

The Korean Society of Applied Science and Technology (한국응용과학기술학회)
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In vitro, Percutaneous absorption for Rat about cysteine

In vitro에서 시스테인에 대한 흰쥐의 경피 흡수

  • Jung, Duck-Chae (Department of chemistry, University of Incheon) ;
  • Oh, Eun-Ha (Department of Industrial Health & Environment, Industrial Safety & Health Bureau, Ministry of Labor) ;
  • Kuk, Won-Kwen (Department of Industrial Health & Environment, Industrial Safety & Health Bureau, Ministry of Labor)
  • 정덕채 (시립인천대학교 자연과학대학 화학과) ;
  • 오은하 (노동부 산업안전국 산업보건환경과) ;
  • 국원근 (노동부 산업안전국 산업보건환경과)
  • Published : 2008.06.30
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Abstract

Chemicals for cosmetics, including skin, the skin absorbs some of the research in the field of science or pharmacy recently, about the environment and the health of the heightened interest in skin absorption, and many other human attributes and absorption evaluation studies are underway in various areas. In this study, The effects of commercial permanent wave products to skin which are composed with cysteine and bases using rat. Results are as follows; the content of penetration 4 hours later with steady state and no significant changeable after 20 hours later. In cysteine groups lag time and permeability coefficient of young skin is 3.32hr and $0.102{\mu}g/cm^2{\cdot}hr$, lag time and permeability coefficient of old skin is 4.04hr and $0.106{\mu}g/cm^2{\cdot}hr$. In conclusion of study lag time and permeability coefficient in old skin and wounded skin are faster than healthy skin. We notified that fine rinkle and rash of skin were changeable in the case of treating with permanent wave drugs than normal skin.

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