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Controversy in Pathophysiology of Rotator Cuff Tear: Degenerative Tear

회전근 개 파열의 병리 생태학에서의 논쟁점: 퇴행성 파열

  • Kim, Young-Kyu (Department of Orthopedic Surgery, Gil Medical Center, Gachon University)
  • 김영규 (가천의과학대학교 길병원 정형외과학교실)
  • Published : 2008.12.15

Abstract

The pathophysiology of rotator cuff tears and the progression of asymptomatic tears to symptomatic tears are yet unclear and much controversy. It is likely to involve a number of factors such as a genetic predisposition, extrinsic impingement from structures surrounding the cuff and intrinsic degeneration from changes within the tendon itself. Degenerative changes in the rotator cuff with aging seem to be related to the anatomic and mechanical environment of the rotator cuff. The histopathologic appearance of rotator cuff tendon rupture specimens demonstrates a consequence of degenerative changes at the site of tendon insertion into bone. It weakens the tensile strength of the tendon. Is the process of degeneration intrinsic or extrinsic in nature? I suggest that degeneration is intrinsic and not caused by extrinsic factors. Even though, rotator cuff tear may be secondary to multiple factors, I believe that primary cause of rotator cuff tears is preexisting degenerative change.

회전근 개 파열의 병리 생태와 증상이 없는 파열이 증상이 있는 파열로의 진행 과정은 아직 불분명하여 많은 논란이 있다. 이는 유전적 소인, 회전근 개를 싸고 있는 조직의 외인성 충돌, 건 자체 내의 내인성 퇴행성 변성과 같은 여러 요소들이 관여한다. 연령의 증가에 따른 회전근 개의 퇴행성 변화는 회전근 개의 해부학 및 역학적 환경과 관련이 깊다. 또한 파열된 회전근 개 표본의 조직 병리 소견으로 골에 부착되는 건의 기시부에서는 퇴행성 변성이 나타나며 이러한 현상은 건의 신장력을 약화시키게 된다. 건의 퇴행성 변성의 진행이 내인성이냐 외인성이냐의 의문에 대해 저자는 내인성에 의해 퇴행성 변성이 진행된다고 생각하며 비록 회전근 개 파열이 여러 요소에 의해 이차적으로 발생되기는 하나, 회전근 개 파열의 일차적 원인은 존재하는 퇴행성 변화일 것으로 사료된다.

Keywords

References

  1. Bigliani LU, Morrison D, April EW: The morphology of the acromion and its relationship to rotator cuff tears. Orthop Trans, 10: 228, 1986.
  2. Blaine TA, Kim YS, Voloshin I, et al: The molecular pathophysiology of subacromial bursitis in rotator cuff disease. J Shoulder Elbow Surg, 14: 84-89, 2005. https://doi.org/10.1016/j.jse.2004.09.022
  3. Brewer BJ: Aging of the rotator cuff. Am J Sports Med, 7: 102-110, 1979. https://doi.org/10.1177/036354657900700206
  4. Brooks CH, Revell WJ, Heatley FW: A qualtitative histological study of the vascularity of the rotator cuff tendon. J Bone Joint Surg Br, 74: 151-153, 1992.
  5. Burns WC II, Whipple TL: Anatomic relationships in the shoulder impingement syndrome. Clin Orthop Relat Res. 294: 96-102, 1993.
  6. Chang Y, Hughes RE, Su FC, Itoi E, An KN: Prediction of muscle force involved in shoulder internal rotation. J Shoulder Elbow Surg, 9: 188-195, 2000. https://doi.org/10.1016/S1058-2746(00)90054-5
  7. Codman EA: The shoulder. Boston: Thomas Todd, 98, 1934.
  8. Fukuda H, Hamada K, Yamanaka K: Pathology and pathogenesis of bursal-side rotator cuff tears viewed from en bloc histologic sections. Clin Orthop Relat Res, 254: 75-80, 1990.
  9. Fukuda H, Hamada K, Nakajima T, Tomonaga A: Pathology and pathogenesis of the intratendinous tearing of the rotator cuff viewed from en bloc histologic sections. Clin Orthop Relat Res, 304: 60-67, 1994.
  10. Gotoh M, Hamada K, Yamakawa H, et al.: Increased substance P in subacromial bursa and shoulder pain in rotator cuff diseases. J Orthop Res, 16: 618-621, 1998. https://doi.org/10.1002/jor.1100160515
  11. Hashimoto T, Nobuhara K, Hamada T: Pathologic evidence of degeneration as a primary cause of rotator cuff tear. Clin Orthop Relat Res. 415: 111-120, 2003. https://doi.org/10.1097/01.blo.0000092974.12414.22
  12. Huang CY, Wang VM, Pawluk RJ, et al.: Inhomogeneous mechanical behavior of the human supraspinatus tendon under uniaxial loading. J Orthop Res, 23: 924-930, 2005. https://doi.org/10.1016/j.orthres.2004.02.016
  13. Itoi E, Berglund Lj, Grabowski JJ: Tensile propertiens of the supraspinatus tendon. J Orthop Res, 13: 578-584, 1995. https://doi.org/10.1002/jor.1100130413
  14. Kim YS, Bigliasi LV, Fujisawa M, et al: Stromal cell?derived factor 1(SDF-1, CXCL 12) is increased in subacromial bursitis and downregulated by steroid and nonsteroidal anti-inflammatory agents. J Orthop Res, 24: 1756-1764, 2006. https://doi.org/10.1002/jor.20197
  15. Kumagai J, Sarkar K, Uhthoff HK: The collagen typed in the attachment zone of rotator cuff tendons in the elderly: An immunohistochemical study. J Rheumatol, 21: 2096-2100, 1994.
  16. Lee SB, Nakajima T, Luo ZP, Zobitz ME, Chang YW, An KN: The bursal and articular sides of the supraspinatus tendon have a different compressive stiffness. Clin Biomech, 15: 241-247, 2000. https://doi.org/10.1016/S0268-0033(99)00086-8
  17. Loew M: Traumatic development of rotator cuff lesion. Scientific principles and consequences for export assessment. Orthopedics. 29: 881-887, 2000.
  18. Lohr JF, Uhthoff HK: The microvascular pattern of the supraspinatus tendon. Clin Orthop Relat Res, 254: 35-38, 1990.
  19. Longo UG, Franceschi F, Ruzzini L, et al: Histopathology of the supraspinatus tendon in rotator cuff tears. Am J Sports Med, 36: 533-538, 2008.
  20. Luo ZP, Hsu HC, Grabowski JJ, Morrey BF, An KN: Mechanical environment associated with rotator cuff tears. J Shoulder Elbow Surg, 7:616-620, 1998. https://doi.org/10.1016/S1058-2746(98)90010-6
  21. Neer CS 2nd: Anterior acromioplasty for the chronic impingement syndrome in the shoulder. J Bone Joint Surg Am, 45: 41-50, 1972.
  22. Nobuhara K: Injury of the rotator cuff. In: The shoulder. 1st ed. World Scientific Publishing Co: 202-219.
  23. Rathbun JB, Macnab I: The microvascular pattern of the rotator cuff. J Bone Joint Surg Br, 52: 540-553, 1970.
  24. Ryu RKN: Arthroscopic management of partial tears of the rotator cuff. Instr Course Lect at 21st annual meeting, Arthroscopy Association of North America, Washington DC, 580-586, 2002.
  25. Soslowski LJ, Carpenter JE, DeBano CM, Banerji I, Moalli MR: Development and use of an animal model for investigations on rotator cuff disease. J Shoulder Elbow Surg, 5: 383-392, 1996. https://doi.org/10.1016/S1058-2746(96)80070-X
  26. Tempelhof S, Rupp S, Seil R: Age-related prevalence of rotator cuff tears in asymptomatic shoulders. J Shoulder Elbow Surg, 8: 296-299, 1999. https://doi.org/10.1016/S1058-2746(99)90148-9
  27. Uhthoff HK, Sarkar K: The effect of aging on the soft tissues of the shoulder. In Matsen FA III, Fu FH, Hawkins RJ: The Shoulder: A Balance of Mobility and stability. Rosement, IL: American Academy of Orthopaedic Surgeons, 269-278, 1993.
  28. Wakabayashi I, Itoi E, Sano H, et al: Mechanical environment of the supraspinatus tendon: A two-dimensional finite element model analysis. J Shoulder Elbow Surg. 12: 612-617, 2003. https://doi.org/10.1016/S1058-2746(03)00214-3

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