Natural Product Sciences

The Korean Society of Pharmacognosy (한국생약학회)
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Microbial Transformation of Isoxanthohumol, a Hop Prenylflavonoid

  • Kim, Hyun-Jung (College of Pharmacy and Research Institute of Drug Development, Chonnam National University) ;
  • Kang, Min-Ah (College of Pharmacy and Research Institute of Drug Development, Chonnam National University) ;
  • Lee, Ik-Soo (College of Pharmacy and Research Institute of Drug Development, Chonnam National University)
  • Published : 2008.12.31
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Abstract

Microbial transformation of isoxanthohumol (1), a prenylated flavanone from hops, has resulted in the production of a pair of glucosylated derivatives. The structures of these compounds were elucidated to be (2S)-5-methoxy-8-prenylnaringenin 7-O-${\beta}$-D-glucopyranoside (2) and (2R)-5-methoxy-8-prenylnaringenin 7-O-${\beta}$-Dglucopyranoside (3) based on the spectroscopic analyses.

Keywords

References

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