Spontaneous Pneumomediastinum Accompanied by Bleomycin-Induced lung Toxicity

Bleomycin 유도 폐독성에 동반된 자연성 종격동 기종

  • Do, Young-Woo (Department of Thoracic and Cardiovascular Surgery, Kyungpook National University Hospital, Kyungpook National University College of Medicine) ;
  • Cho, Suk-Ki (Department of Thoracic and Cardiovascular Surgery, Kyungpook National University Hospital, Kyungpook National University College of Medicine) ;
  • Lee, Young-Ok (Department of Thoracic and Cardiovascular Surgery, Kyungpook National University Hospital, Kyungpook National University College of Medicine) ;
  • Lee, Eung-Bae (Department of Thoracic and Cardiovascular Surgery, Kyungpook National University Hospital, Kyungpook National University College of Medicine)
  • 도영우 (경북대학교 의과대학 부속병원 흉부외과학교실) ;
  • 조석기 (경북대학교 의과대학 부속병원 흉부외과학교실) ;
  • 이영옥 (경북대학교 의과대학 부속병원 흉부외과학교실) ;
  • 이응배 (경북대학교 의과대학 부속병원 흉부외과학교실)
  • Published : 2008.12.05

Abstract

Pneumomediastinum is a rare, but well recognized complication of bleomycin-induced lung toxicity. Spontaneous pneumomediastinum has to be considered as one of the causes when the dyspnea becomes aggravated in patients with bleomycin induced lung toxicity. We describe here two patients who suffered with germ cell tumor and they developed spontaneous pneumomediastinum without pneumothorax, and this was caused by bleomycin-induced lung toxicity.

Bleomycin에 의한 폐독성은 잘 알려져 있으나, Bleomycin 유도 폐독성 후에 기흉 없이 발생한 자연성 종격동 기종은 드문 것으로 알려져 있다. 따라서, Bleomycin 항암 치료를 받은 환자에서 호흡 곤란의 악화 원인으로 자연성 종격동 기종도 고려해야 할 필요가 있다. 저자들은 생식 세포종으로 Bleomycin 항암치료를 받은 후 심한 호흡곤란을 호소하는 두 명의 환자에서 기흉이 없는 자연성 종격동 기종을 진단하고 치료 하였기에 보고하는 바이다.

Keywords

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