전북지역 육용오리에서 고병원성 조류인플루엔자 발생 증례

Occurrence of highly pathogenic avian influenza from domestic ducks in Jeonbuk province

  • 추금숙 (전라북도 축산위생연구소 정읍지소) ;
  • 강미선 (전라북도 축산위생연구소 정읍지소) ;
  • 조범준 (전라북도 축산위생연구소 정읍지소) ;
  • 이정원 (전라북도 축산위생연구소 정읍지소)
  • Chu, Keum-Suk (Jeongeup-Branch Jeonbuk Institute of Livestock & Veterinary Research) ;
  • Kang, Mi-Seon (Jeongeup-Branch Jeonbuk Institute of Livestock & Veterinary Research) ;
  • Cho, Bum-Jun (Jeongeup-Branch Jeonbuk Institute of Livestock & Veterinary Research) ;
  • Lee, Jeong-Won (Jeongeup-Branch Jeonbuk Institute of Livestock & Veterinary Research)
  • 발행 : 2008.09.30

초록

Highly pathogenic avian influenza(HP AI) is one of the most important zoonoses in the around of world. That occurred in the domestic ducks of 34 olds day in Jeonbuk of Korea on April 2008. All of infected ducks were died. We could found several clinical signs such as facial swelling with cloudy eyes, conjunctivitis, and neurological sign. In the autopsy, moderate congestion in the kidney, multifocal hemorrhagic foci in pancreas, and mild swelling in brain were observed. Gliosis in brain and severe congestion in kidney were also shown in histopathological findings. Specific band for H5 antibody was detected in polymerase chain reaction (PCR).

키워드

참고문헌

  1. http://www.who.int/csr/disease/avian_influenza/country/cases_table_2008_06_19/en/index.html
  2. http://kreisun.krei.re.kr/kor/issue/quick_view.php?reportid=PR00050&rclass=j&keyword=조류인플루엔자&cpage=1&skey=&sword=
  3. Calnek BW, Barnes HJ, Beard CW, et al. 2003. Diseasess of poultry, 11eds. Iowa State University Press, Ames, Iowa: 135-160
  4. De Jong MD, Hien TT. 2006. Avian influenza A(H5N1). J Clin Virol 35(1):2-13 https://doi.org/10.1016/j.jcv.2005.09.002
  5. Govorkova EA, Leneva IA, Goloubeva OG, et al. 2001. Comparisons of effica-cies of RWJ270201, zanamivir, and oselra-mivir against H5N1, H9N2, and other avian influenza viruses. Antimicrob Agents Chemother 45(10):2723-2732 https://doi.org/10.1128/AAC.45.10.2723-2732.2001
  6. Guan Y, Shortridge KF, Krauss S, et al. 1999. Molecular characterization of H9N2 influenza viruses: Were they the donors of the "internal" genes of H5N1 viruses in Hong Kong. Microbiology 96(16):363-367
  7. http://www.fao.org/docs/eims/upload//210749/Gui_principlesHPAI_july04_en.pdf
  8. Hoffmann E, Stech J, Leneva I, et. al. 2000. Characterization of the Influenza A virus gene pool in avian species in southern China: Was H5N1 a aerivative or a precursor of H5N1?. J Virol 74(14):6309-6315 https://doi.org/10.1128/JVI.74.14.6309-6315.2000
  9. Suarez DL, Perdue ML, Cox N, et al. 1998. Comparisons of highly virulent H5N1 influenza A viruses isolated from Hong Kong. J Virol 72(8):6678-6688
  10. Angela N, Cauthen DE. Swayne SSC, et al. 2000. Continued circulation in China of highly pathogenic avian influenza viruses encoding the hemagglutinin gene associ-ated with the 1997 H5N1 outbreak in poultry and humans. J Virol 47(14):6592-6599
  11. Horimoto T, Kaswaoka Y. 2001. Pan-demic threat posed by avian influenza A viruses. Clin Microbiol Rev 14(1):129-149 https://doi.org/10.1128/CMR.14.1.129-149.2001
  12. Fouchier MD, Munster V, Wallensten A, et al. 2005. Characterization of a novel influenza a virus hemagglutinin subtype(H16) obtained from black-headed gull. J Virol 79(5):2814-2822 https://doi.org/10.1128/JVI.79.5.2814-2822.2005
  13. Brown IH, Osterhaus DM, Fouchier RA, et al. 2007. Genetic characterization of HPAI (H5N1) viruses from poultry and wild vultures, Burkina Faso. Emerg Infect Dis 13(4) : 611-613 https://doi.org/10.3201/eid1304.061356
  14. Schild GC, Oxford JS, Newman RW. 1981. Evidence for antigenic variation in influenza A nucleoprotein. Virology 93(2):569-573 https://doi.org/10.1016/0042-6822(79)90259-9
  15. http://www.fao.org/avianflu/en/index.html
  16. Duan L, Campitelli L, Fan XH, et al, 2007. Characterization of low-pathogenic H5 subtype influenza viruses from Eurasia: Implications for the origin of highly pathogenic H5N1 virues. J Virol 81(14):7529-7539 https://doi.org/10.1128/JVI.00327-07
  17. Pantin-Jackwood MJ, Suarez DL, Spack-man E, et, al. 2007. Age at infection affects the pathogenicity of Asian highly pathogenic avian influenza H5N1 viruses in ducks. Virus Res 130(1-2) : 151-161 https://doi.org/10.1016/j.virusres.2007.06.006
  18. Sturm-Ramirez KM, Ellis T, Bousfield B, et al. 2004. Reemerging H5N1 influenza viruses in Hong Kong in 202 are highly pathogenic to duck. J Virol 78(9) : 4892-4901 https://doi.org/10.1128/JVI.78.9.4892-4901.2004
  19. Lee CW, Suarez DL, Yumpey TM, et, al. 2005. Characterization of highly patho-genic H5N1 avian influenza A viruses isolated from South Korea. J Virol 79(6) : 3692-3702 https://doi.org/10.1128/JVI.79.6.3692-3702.2005
  20. 김용주, 이윤정, 정옥미 등. 2007. 국내 발생 고병원성 조류 인플루엔자의 특성. 한국공중보건학회지 31(2) : 193-202
  21. Webster RG, Hulse-Post D, Sturm-Ramirez KM, et, al. 2007. Changing epi-demiology and ecology of highly patho-genic avian H5N1 influenza viruses. Avian Dis 51(1 Suppl) : 269-272 https://doi.org/10.1637/7641-050206R.1
  22. Chen HD, Deng G, Li Z, et al. 2004. The evolution of influenza a virus in ducks in southern China. Proc Natl Acad Sci USA 101(28) : 10452-10457