The Journal of Korean Obstetrics and Gynecology (대한한방부인과학회지)

The Society of Korean Medicine Obstetrics and Gynecology (대한한방부인과학회)
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Short term effect of Allii tuberosi semen on muscular fatigue and muscular strength

단기간(短期間)의 구자 투여(投與)가 생쥐의 근피로(筋疲勞)와 근력(筋力)에 미치는 영향(影響)

  • Lee, Jin-Moo (Dept. of Oriental Gynecology, College of Oriental Medicine, KyungHee Univ.) ;
  • Lee, Chang-Hoon (Dept. of Oriental Gynecology, College of Oriental Medicine, KyungHee Univ.) ;
  • Cho, Jung-Hoon (Dept. of Oriental Gynecology, College of Oriental Medicine, KyungHee Univ.) ;
  • Jang, Jun-Bock (Dept. of Oriental Gynecology, College of Oriental Medicine, KyungHee Univ.) ;
  • Lee, Kyung-Sub (Dept. of Oriental Gynecology, College of Oriental Medicine, KyungHee Univ.) ;
  • Byun, Sang-Hyun (Dept. of Oriental Gynecology, College of Oriental Medicine, KyungHee Univ.)
  • 이진무 (경희대학교 한의과대학 부인과학교실) ;
  • 이창훈 (경희대학교 한의과대학 부인과학교실) ;
  • 조정훈 (경희대학교 한의과대학 부인과학교실) ;
  • 장준복 (경희대학교 한의과대학 부인과학교실) ;
  • 이경섭 (경희대학교 한의과대학 부인과학교실) ;
  • 변상현 (경희대학교 한의과대학 부인과학교실)
  • Published : 2007.05.29
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Abstract

Purpose: This study was conducted to investigate the muscle anti-fatigue effects of Allii tuberosi semen after short term administration. Methods: 4-6 weeks old ICR mice were used in this study and we administered the water soluble extracts of Allii tuberosi semen in the concentration of 1, 10 and 100mg/0.3ml to each 5 mice (ATS group) and same volume of normal saline was administered to 5 mice (control group) once a day for 30 or 60 days. After the administration we performed the swimming exercise test and the grip strength test. And we measured the concentration of glucose and the activity of lactate dehydrogenase in plasma regarded as biochemical indicator related with the muscular fatigue.. Results: In swimming exercise test. 10 and 100mg/0.3ml ATS groups showed increased time compared with relative control group after 30 days administration. But after 60 days adminstration all ATS groups showed increased results. In grip strength test, 100mg/0.3ml ATS group increased grip strength after 30days administration and 10mg/0.3ml ATS group showed increased result after 60days administration. All the results of plasma glucose and lactate dehydrogenase didn't showed statistically significant difference after 30 and 60 days administration. Conclusion: From this study we could find the anti-fatigue effect of Allii tuberosi semen in the muscle strength related test.

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