The Transactions of The Korean Institute of Electrical Engineers (전기학회논문지)

The Korean Institute of Electrical Engineers (대한전기학회)
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The Effects of an RF Plasma and Electric Fields on the Death of G361 Melanoma Cells

RF 플라즈마 및 전기장의 흑색종 (G361 melanoma) 세포에 대한 사멸 효과

  • 손채화 (한국전기연구원 전기물리연구그룹) ;
  • 김규천 (부산대학교 치의학과) ;
  • 이해준 (부산대학교 전자전기통신공학부)
  • Published : 2007.11.01
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Abstract

Micro plasma has been recently studied to investigate the effects on various cells. We study a micro-plasma produced by a plasma needle that is operated with RF power and its effects on G361 melanoma cells. The micro plasma size ranges from sub-mm to several mm at a few watts of RF power. For the bio-medical treatment, low-temperature plasma is obtained and gas temperature is controlled within several tens of degrees $(^{\circ}C)$ in order not to disturb cell activities. Elementary spectroscopic studies to obtain plasma characteristics are presented for Ar and He plasma with different frequencies of RF power. Also the preliminary results of the micro plasma effects on G361 melanoma cells are presented. It was observed that the irradiation of micro plasma induces cell death through the deprivation of tyrosine phosphorylation in the G361 cells.

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