Korea-Australia Rheology Journal

  • 제19권2호
  • /
  • Pages.89-95
  • /
  • 2007
  • /
  • 1226-119X(pISSN)
  • /
  • 2093-7660(eISSN)
한국유변학회 (The Korean Society of Rheology)
권호 표지

In-vitro study on the hemorheological characteristics of chicken blood in microcirculation

  • Ji, Ho-Seong (Department of Mechanical Engineering, Pohang University of Science and Technology) ;
  • Lee, Jung-Yeop (Department of Mechanical Engineering, Pohang University of Science and Technology) ;
  • Lee, Sang-Joon (Department of Mechanical Engineering, Pohang University of Science and Technology)
  • 발행 : 2007.08.31
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

The flow characteristics of chicken blood in a micro-tube with a $100{\mu}m$ diameter are investigated using a micro-Particle Image Velocimetry (PIV) technique. Chicken blood with 40% hematocrit is supplied into the micro-tube using a syringe pump. For comparison, the same experiments are repeated for human blood with 40% hematocrit. Chicken blood flow has a cell-free layer near the tube wall, and this layer's thickness increases with the increased flow speed due to radial migration. As a hemorheological feature, the aggregation index of chicken blood is about 50% less than that of human blood. Therefore, the non-Newtonian fluid features of chicken blood are not very remarkable compared with those of human blood. As the flow rate increases, the blunt velocity profile in the central region of the micro-tube sharpens, and the parabolicshaped shear stress distribution becomes to have a linear profile. The viscosity of both blood samples in a low shear rate condition is overestimated, while the viscosity in a high shear rate range is underestimated due to radial migration and the presence of a cell-depleted layer.

키워드

참고문헌

  1. Baskurt, O.K. and H.J. Meiselman, 2003, Blood rheology and hemodynamics, Seminars in Thrombosis and Hemostasis 29, 435-450
  2. Bishop, J.J, P.R. Nance, A.S. Popel, M. Intaglietta and P.C. Johnson, 2001, Effect of erythrocyte aggregation on velocity profiles in venules, American Journal of Physiology Heart and Circulatory Physiology 280, 222-236 https://doi.org/10.1152/ajpheart.2001.280.1.H222
  3. Cardoso, A.V. and A.O. Camargos, 2002, Geometrical aspects during formation of compact aggregates of red blood cells, Materials Research 5, 263-268 https://doi.org/10.1590/S1516-14392002000300008
  4. Goldsmith, H.L., 1986, The microrheology of human blood, Microvascular Research 31, 121-142 https://doi.org/10.1016/0026-2862(86)90029-4
  5. Hardeman, M.R., J.G.G. Dobbe and C. Ince, 2001, The Laserassisted Optical Rotational Cell Analyzer (LORCA) as red blood cell aggregometer, Clinical Hemorheology and Microcirculation 25, 1-11
  6. Pickart, C, J.M. Piau and H. Galliard, 1998, Human blood shear yield stress and its hematocrit dependence, Journal of Rheology 42, 1-12 https://doi.org/10.1122/1.550883
  7. Singh, M. and N.A. Coulter Jr., 1973, Rheology of blood: Effect of dilution with various dextrans, Microvascular Research 5, 123-130 https://doi.org/10.1016/0026-2862(73)90063-0
  8. Sugii, Y., S. Nishio and K. Okamoto, 2002, In-vivo PIV measurement of red blood cell velocity field in microvessels considering mesentery motion, Physiological Measurement 23, 403-416 https://doi.org/10.1088/0967-3334/23/2/315
  9. Sugii, Y., R. Okuda, K. Okamoto and H. Madarame, 2005, Velocity measurement of both red blood cells and plasma of in vitro blood flow using high-speed micro PIV technique, Meas. Sci. Technol. 16, 1126-1130 https://doi.org/10.1088/0957-0233/16/5/011
  10. Vennemann, P., K.T. Kiger, R. Lindken, B.W. Groenendijk, S.S. Vos, T.M. ten Hagen, N.T.C. Ursem, R.E. Poelmann, J. Westerweel and B. Hierck, 2006, In vivo micro particle image velocimetry measurements of blood-plasma in the embryonic avian heart, Journal of Biomechanics 39, 1191-1200 https://doi.org/10.1016/j.jbiomech.2005.03.015
  11. Windberger, U., A. Bartholovitsch, R. Plasenzotti, K.J. Korak and G. Heinze, 2003, Whole blood viscosity, plasma viscosity and erythrocyte aggregation in nine mammalian species: reference values and comparison data, Experimental Physiology 88, 431-440 https://doi.org/10.1113/eph8802496