Journal of The Korean Society of Clinical Toxicology (대한임상독성학회지)

Korean society of Clincal Toxicology (대한임상독성학회)
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Organophosphate-Pyrethroid Mixtures Poisoning

유기인계-피레스로이드계 혼합제제 농약에 의한 중독

  • Hong, Dae-Young (Department of Emergency Medicine, Konkuk University Hospital) ;
  • Baek, Kwang-Je (Department of Emergency Medicine, Konkuk University Hospital) ;
  • Lee, Kyeong-Ryong (Department of Emergency Medicine, Konkuk University Hospital) ;
  • Kwon, Woon-Yong (Department of Emergency Medicine, Seoul National University College of medicine) ;
  • Park, Joon-Seok (Department of Emergency Medicine, College of Medicine, Konyang University) ;
  • Eo, Eun-Kyung (Department of Emergency Medicine, School of Medicine, Ewha Womans University) ;
  • Oh, Bum-Jin (Department of Emergency Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Lee, Mi-Jin (Department of Emergency Medicine, College of Medicine, The Catholic University of Korea) ;
  • Lee, Sung-Woo (Department of Emergency Medicine, Korea University College of Medicine) ;
  • Suh, Joo-Hyun (Department of Internal Medicine, Gachon University of Medicine and Science) ;
  • Roh, Hyung-Keun (Department of Internal Medicine, Gachon University of Medicine and Science) ;
  • Kim, Jun-Sig (Department of Emergency Medicine, Inha University Hospital)
  • 홍대영 (건국대학교 의과대학 응급의학교실) ;
  • 백광제 (건국대학교 의과대학 응급의학교실) ;
  • 이경룡 (건국대학교 의과대학 응급의학교실) ;
  • 권운용 (서울대학교 의과대학 응급의학교실) ;
  • 박준석 (건양대학교 의과대학 응급의학교실) ;
  • 어은경 (이화여자대학교 의학전문대학원 응급의학교실) ;
  • 오범진 (울산대학교 의과대학 서울아산병원 응급의학교실) ;
  • 이미진 (가톨릭대학교 의과대학 응급의학교실) ;
  • 이성우 (고려대학교 의과대학 응급의학교실) ;
  • 서주현 (가천의과학대학교 내과학교실) ;
  • 노형근 (가천의과학대학교 내과학교실) ;
  • 김준식 (인하대학교 의과대학 응급의학교실)
  • Published : 2007.06.13
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Abstract

Purpose: Owing to organophosphate-pyrethroid mixtures are widely used, suicidal or unintentional poisoning is common. But there have been relatively few reports of poisoning. The purpose of this study is to evaluate the difference of the severity and toxicity between organophosphate-pyrethroid mixtures poisoning and single organophosphate poisoning. Methods: From August 2005 to July 2006, 65 patients presented with organophosphate-pyrethroid mixtures poisoning to emergency medical center. Date were gathered by report form it was drawn up. Results: 65 patients were enrolled in 28 hospitals and their mean age was $56.5{\pm}16.2$ years old. The most common cause of poisoning was suicide, in 52 cases(80%). Chlorpyrifos-cypermethrin, malathion-esfenvalerate were the most frequent chemicals involved, and the mean ingestion amount was 135.4ml. The most common symptom of the patients was nausea/vomiting, in 16 patients. The average GCS score was 13. The mean ICU stay was $4.4{\pm}5.2$ days, and mortality was 3.1%. Conclusion: The severity and toxicity of organophosphate-pyrethroid mixture poisoning were lower than that of single organophosphate poisoning.

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