Journal of Preventive Medicine and Public Health

The Korean Society for Preventive Medicine (대한예방의학회)
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Body Mass Index and Risk of Hemorrhagic Stroke in Korean Adults: Case-control Study

체질량지수와 출혈성 뇌졸중 발생간의 관련성에 대한 환자-대조군연구

  • Kim, Seon-Ha (Department of Preventive Medicine, Seoul National University College of Medicine) ;
  • Lee, Yong-Seok (Department of Neurology, Seoul National University Boramae Hospital) ;
  • Lee, Seung-Mi (Department of Preventive Medicine, Seoul National University College of Medicine) ;
  • Yoon, Byung-Woo (Department of Neurology, Seoul National University College of Medicine) ;
  • Park, Byung-Joo (Department of Preventive Medicine, Seoul National University College of Medicine)
  • 김선하 (서울대학교의과대학 예방의학교실) ;
  • 이용석 (서울시립보라매병원 신경과) ;
  • 이승미 (서울대학교의과대학 예방의학교실) ;
  • 윤병우 (서울대학교의과대학 신경과학교실) ;
  • 박병주 (서울대학교의과대학 예방의학교실)
  • Published : 2007.07.31
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Abstract

Objectives : To evaluate the association between body mass index (BMI) and hemorrhagic stroke. Methods : A case-control study was conducted on 2,712 persons (904 cases, 904 hospital controls, and 904 community controls) participating in an Acute Brain Bleeding Analysis study from October 2002 to March 2004. Two controls for each case were matched according to age and gender. The information was obtained by trained interviewers using standardized questionnaire. A conditional logistic regression model was used to estimate the association between BMI and the frequency of having a hemorrhagic stroke. Results : Obese men (25.0 $\leq$ BMI < $30.0\;kg/m^2$) had an odds ratios (OR) of 1.39 (95% CI 1.03 to 1.87) a hemorrhagic stroke, compared to men with a normal BMI (18.5 to $24.9\;kg/m^2$). Conversely, women with lower BMI had a higher risk of having hemorrhagic stroke. With respect to subtypes of hemorrahagic stroke, we observed about a three-fold increase in the risk of intracerebral hemorrhage (ICH) in the highly obese group. However, these trends were not significant in patients with subarachnoid hemorrhages. Conclusions : Obesity was identified as one of the risk factors in hemorrhagic stroke, in particular ICH. Conversely, in women, a lean body weight increases the risk of hemorrhagic stroke. Consequently, managing one's weight is essential to reduce the risks of hemorrhagic stroke.

Keywords

References

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