Biomolecules & Therapeutics

The Korean Society of Applied Pharmacology (한국응용약물학회)
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Molecular Events on Experimental Skin Inflammation and Modulation by Topical Anti-inflammatory Flavonoids

  • Kim, Hyun-Pyo (College of Pharmacy, Kangwon National University)
  • Published : 2007.03.30
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Abstract

There have been various animal models of skin inflammation. These models have been used for establishing anti-inflammatory activity of the topical agents including cosmetics. Here, the molecular mechanisms of most widely-used animal models of skin inflammation including contact irritation, acute and chronic inflammation, and delayed-type hypersensitivity are summarized. Against these animal models, varieties of plant flavonoids showed anti-inflammatory activity. The action mechanisms of anti-inflammation by topical flavonoids are presented. A therapeutic potential of flavonoids is discussed.

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References

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