대한예방한의학회지 (Journal of Society of Preventive Korean Medicine)
- 제11권1호
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- Pages.9-21
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- 2007
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- 1226-7066(pISSN)
랫드의 두개골세포 활성 및 mRNA 발현에 미치는 홍화자의 영향
Effects of Carthami Tinctorius on Rat Calvarial Cell Activity and MG63 Cell mRNA Synthesis
- Kim, Tae-Woong (College of Oriental Medicine, Kyungwon University) ;
- Hwang, Gwi-Seo (College of Oriental Medicine, Kyungwon University)
- 발행 : 2007.06.30
초록
This study was performed to evaluate the effect of Carthami tinctorius(HH) on osteoblast function and gene expression. The osteoblasts separated from the rat calvariae were cultivated to evaluate the cell function, and MG-63 cell was also cultivated for the test of mRNA synthesis. In this experiments, cell proliferation of rat calvarial cells was increased by HH. PKC activity, intracellular free calcium level and collgen synthesis from calvarial cells were increased by HH, but not PKA activity. And the mRNA of