3차 군병원 응급실에 내원한 국군 병사들의 파상풍 항체의 정성적 조사

Qualitative Analysis of the Tetanus Antibody in Korean Army personnel after Visiting a Tertiary Armed Forces Hospital

  • 김정권 (가천의과대학 부속 길병원 응급의학과) ;
  • 신종환 (서울대학교 보라매병원 응급의학과)
  • Kim, Chung Kwon (Department of Emergency Medicine, Gachon University Gil Medical Center) ;
  • Shin, Jong Hwan (Department of Emergency Medicine, Seoul National University Boramae Hospital)
  • 투고 : 2007.06.22
  • 심사 : 2007.12.24
  • 발행 : 2007.12.30

초록

Purpose: In the Korean armed forces, vaccination against tetanus is done when personnel join the military service, but we do not know how many military personnel are vaccinated and how many soldiers have protection against tetanus. We performed a qualitative analysis of the tetanus antibody in Korean military personnel by using the TQS (Tetanus Quick Stick) Methods: This study used a prospective collection method for military personnel visiting to the emergency department of a tertiary armed forces hospital from July 2005 to January 2007. We performed an analysis by using the TQS and asked whether the personnel had been inoculated during military service. Results: The number of enrolled military personnel was 474. Among them, 412 had been vaccinated against tetanus after entering the military service. The positive rate of TQS was 91.3% (373 patients) after vaccination for tetanus. Conclusion: Many military personnel were inoculated with tetanus toxoid during military service and have protective antibodies for tetanus. According as TQS should be used for military personnel who visit the emergency department of an armed forces hospital. Also, anti-tetanus immunoglobulin should not normally be used a positive TQS for tetanus prophylaxis.

키워드

참고문헌

  1. Kim HJ, Kang GH, Kim KW, Kim SC, Kim YS, Kim CH, et al. Korean multicenter study of tetanus antibody titer. J Korean Soc Emerg Med 2005;16:667-76
  2. Yoon YS, Kim EC, Lee WH, Chung SW, Yi JH, Park IC, et al. Utility of tetanus quick stick test for selective tetanus prophylaxis. J Korean Soc Emerg Med 2004;15:95-101
  3. Sohn YD, Lim KS, Choi WJ, Ahn JY, Kim W, Choi YB, et al. Qualitative analysis of anti-tetanus antibody titers in korean. J Korean Soc Trauma 2004;17:27-36
  4. Espinoza P, Colombet I, Saguez C, Sanson-Le P, Coudert B, Chatellier G. Diagnosis of tetanus immunization status: multicenter assessment of a rapid biological test. Eur J Emerg Med 2005;12(4):209
  5. Elkharrat D, Cantaloube N, Sanson-Le-Pors MJ, Benhamou F, Arrouy L. Validation of a rapid test to predict tetanus immunity in patients presenting with wounds in an emergency department: a prospective concordance study of 1018 patients. Eur J Emerg Med 2005;12:207
  6. Stubbe M, Swinnen R, Crusiaux A, Mascart F, Lheureux P. Seroprotection against tetanus in patients attending an emergency department in Belgium and evaluation of a bedside immunotest. Eur J Emerg Med 2007;14:14-24 https://doi.org/10.1097/01.mej.0000228449.37974.7e
  7. http://www.cdc.gov/nip/publications/pink/tetanus.pdf
  8. Center For Disease Control and Prevention: Tetanus Surveillance-United States, 1995-1997. MMWR Morb Mortal Wkly Rep 1998;47:1-11
  9. Center For Disease Control and Prevention: Tetanus Surveillance-United States, 1998-2000. MMWR Morb Mortal Wkly Rep 2003;52:1-8
  10. Korea Center of Disease Control and Prevention (KCDC) Report. 1998-2006
  11. Recommended childhood immunization schedule United States, 2001. MMWR Morb Mortal Wkly Rep 2001;50:7-10
  12. Center for Disease Control. Diphtheria, tetanus, and pertussis: Recommendations for vaccine use and other preventive measures recommendations of the immunization practices advisory committee (ACIP). MMWR Morb Mortal Wkly Rep 1991;40:1-28
  13. Rhee P, Nunley MK, Demetriades D, Velmahos G, Doucet JD. Tetanus and trauma: a review and recommendations. J Trauma 2005;58:1082-8 https://doi.org/10.1097/01.TA.0000162148.03280.02
  14. Cho HJ, Hong MG, Lee JH, Won JU, Kim SM, Youn BB. A study of knowledge practice rates of adult immunization. J Korean Acad Fam Med 1994;15:535-45
  15. Kim KC, Kim CH, Kim HJ, Jeon IS, Seo HK. Doctor's prescription behavior for tetanus prophylaxis in wound management. J Korean Acad Fam Med 1996;17:492-500
  16. Ha YR, Goo HD, Kim SH, Jang SJ, Lee HS, Shim HS, et al. Antitetanus antibody titers after toxoid injection. J Korean Soc Emerg Med 1996;7:202-6
  17. Kang JH, Hur JK, Kim JH, Lee KH, Park SE, Ma SH, et al. Age related immunoseroepidemiological study to tetanus and pertussis in Korean population. J Korean Soc Infect Dis 2001;33:104-11
  18. Han HY, GO UY, Kim SS, Jeong GT, Yu JS, Yu CG, et al. Seroprevalence of diphtheria and tetanus antibodies and considerations on the Td booster vaccination aomong adults in republic of korea. The report of national institute of health 2003;40:266-7